2-Propanesulfonyl chloride
2-Propanesulfonyl chloride (CAS: 10147-37-2) is a sulfur-containing organic compound with the linear formula (CH3)2CHSO2Cl and a molecular weight of 142.60 g/mol. This reactive sulfonyl halide serves as a valuable building block in organic synthesis, particularly for introducing the isopropylsulfonyl group into various molecules. It is employed in chemical research and development for creating complex organic structures and intermediates.

Organic Synthesis Intermediate
2-Propanesulfonyl chloride is utilised as a key intermediate in the synthesis of a wide range of organic compounds. Its reactivity allows for the facile introduction of the isopropylsulfonyl moiety, enabling the construction of diverse molecular architectures.
Building Block in Chemical Research
This compound acts as a fundamental building block in academic and industrial research settings. It is instrumental in the development of new synthetic methodologies and the exploration of novel chemical entities.
Sulfonylation Reagent
As a sulfonyl halide, it functions as an effective sulfonylation reagent, reacting with nucleophiles to form sulfonamides, sulfonates, and other sulfur-containing functional groups.
| Molecular weight | 142.60 |
|---|---|
| Linear formula | (CH3)2CHSO2Cl |
| Assay | ≥97.0% (GC) |
| Boiling point | 74-75 °C/19 mmHg(lit.) |
| Density | 1.27 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.453(lit.)n20/D 1.455 |
| Vapour pressure | 15.5 mmHg (25 °C) |
| Vapour density | 4 (vs air) |
| Autoignition temp | 865 °F |

Hazard statements
- H314Causes severe skin burns and eye damage
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Propanesulfonyl chloride used for?
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2-Propanesulfonyl chloride is primarily used as a building block in organic synthesis and as an intermediate for creating various organic compounds, particularly those requiring the introduction of an isopropylsulfonyl group.
What is the CAS number and formula for 2-Propanesulfonyl chloride?
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The CAS number is 10147-37-2, and its linear formula is (CH3)2CHSO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Propanesulfonyl chloride with an assay of ≥97.0% (GC). We do not represent this product as USP, EP, BP, or any other pharmacopoeia grade.
How should 2-Propanesulfonyl chloride be handled?
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2-Propanesulfonyl chloride is classified as Danger (GHS05) with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including full-face respirators, gloves, and goggles, is essential. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
How is 2-Propanesulfonyl chloride packed and shipped?
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It is shipped under UN 3265, Class 8, Packing Group II. Packaging is designed to ensure safe transport and compliance with international shipping regulations.
How can I request a sample or quote for 2-Propanesulfonyl chloride?
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To request a sample or a quote, please contact our sales department via the website or telephone, providing your specific requirements and shipping details.
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