2-Piperidineethanol
2-Piperidineethanol (CAS: 1484-84-0; Formula: C7H15NO) is a versatile heterocyclic building block with a molecular weight of 129.20 g/mol. This compound serves as a key reactant in the synthesis of various biologically active molecules. Its applications span the development of pharmaceuticals, including Spiroimidazolidinone NPC1L1 inhibitors, P2Y12 antagonists, and cyclin-dependent kinase inhibitors. It is also utilized in the creation of anti-HIV agents and tetraponerine analogues.
- IUPAC
- 2-(2-Hydroxyethyl)piperidine
Synthesis of Spiroimidazolidinone NPC1L1 Inhibitors
2-Piperidineethanol is employed as a crucial reactant in the multi-step synthesis of Spiroimidazolidinone NPC1L1 inhibitors, which are investigated for their therapeutic potential.
Development of P2Y12 Antagonists
This compound acts as a precursor in the synthesis of P2Y12 antagonists. These molecules are studied for their ability to inhibit platelet aggregation, making them relevant in cardiovascular research.
Preparation of Cyclin-Dependent Kinase Inhibitors
The chemical structure of 2-Piperidineethanol lends itself to its use as a reactant in the creation of novel cyclin-dependent kinase (CDK) inhibitors.
Synthesis of Anti-HIV Agents
As a valuable building block, 2-Piperidineethanol is incorporated into synthetic routes aimed at developing new anti-HIV therapeutic agents.
Cyclization Reactions
It serves as a reactant in cyclization processes, specifically for the formation of secondary homoallylic amines, expanding its utility in organic synthesis.
| Molecular weight | 129.20 |
|---|---|
| Empirical formula | C7H15NO |
| Assay | 90% |
| Boiling point | 234 °C(lit.) |
| Application | Reactant for syntehsis of: Spiroimidazolidinone NPC1L1 inhibitors1 P2Y12 antagonists for inhibition of platelet aggregation2 Cyclin-dependent kinase inhibitors3 Anti-HIV agents4 Tetraponerine analogs5Reactant for cyclization of secondary homoallylic amines6 |
| Melting point | 38-40 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 112 °C / 233.6 °F |
| Transport (UN / ADR) | UN 3263 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Piperidineethanol used for?
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2-Piperidineethanol (CAS: 1484-84-0) is primarily used as a reactant in the synthesis of various compounds, including Spiroimidazolidinone NPC1L1 inhibitors, P2Y12 antagonists, cyclin-dependent kinase inhibitors, anti-HIV agents, and tetraponerine analogues. It is also used in the cyclization of secondary homoallylic amines.
What is the CAS number and formula for 2-Piperidineethanol?
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The CAS number for 2-Piperidineethanol is 1484-84-0, and its empirical formula is C7H15NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Piperidineethanol with an assay of 90%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should 2-Piperidineethanol be handled safely?
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2-Piperidineethanol is classified as corrosive and harmful if swallowed, inhaled, or in contact with skin. It causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., N100 respirator), must be used. Handle only in well-ventilated areas and seek immediate medical attention in case of exposure.
How is 2-Piperidineethanol typically packed and exported?
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As a specialist global supplier, Tech Serve Solutions ensures appropriate packaging for the safe handling, storage, and export of chemicals like 2-Piperidineethanol, adhering to international shipping regulations.
How can I request a sample or a quote for 2-Piperidineethanol?
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To request a sample or a quote for 2-Piperidineethanol, please contact the Tech Serve Solutions sales department through our website or by phone, providing your specific requirements.
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