2-Piperidinoethyl isothiocyanate
2-Piperidinoethyl isothiocyanate (CAS: 32813-24-4) is a chemical compound with the formula C8H14N2S and a molecular weight of 170.28 g/mol. This isothiocyanate derivative serves as a valuable building block in organic synthesis. Its primary applications involve the preparation of various heterocyclic compounds, including urea and thiourea derivatives, which have demonstrated utility in antimalarial research and as antagonists for neuropeptides.
- IUPAC
- 1-(2-Isothiocyanatoethyl)-piperidine,2-(1-Piperidinyl)ethyl isothiocyanate
Synthesis of Antimalarial Agents
This compound is utilized as a reactant in the synthesis of urea and thiourea derivatives, which have been investigated for their potential as antimalarial chemotherapeutics. The isothiocyanate group readily reacts with amines to form these essential linkages.
Neuropeptide Antagonists
2-Piperidinoethyl isothiocyanate serves as a precursor in the development of neuropeptides S antagonists. These compounds are crucial for understanding and modulating neurological pathways.
N-Substituted Imidazole Preparation
The reactivity of the isothiocyanate moiety allows for its use in the synthesis of N-substituted imidazoles, a class of heterocyclic compounds with diverse applications in medicinal chemistry and materials science.
Thio-containing Compound Synthesis
As a versatile building block, it facilitates the construction of various thio-containing organic molecules, expanding the scope of synthetic possibilities for researchers.
| Molecular weight | 170.28 |
|---|---|
| Empirical formula | C8H14N2S |
| Assay | 95% |
| Boiling point | 104-105 °C(lit.) |
| Density | 1.030 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5350(lit.) |
| Storage temperature | 2-8°C |
| Application | Reactant for synthesis of:• Urea and thiourea derivatvies as antmalarial chemotherapeutics1• Neuropeptides S antagonist2• N-substituted imidazoles3• Thio-containing compounds4 |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Piperidinoethyl isothiocyanate used for?
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2-Piperidinoethyl isothiocyanate is used as a reactant for the synthesis of urea and thiourea derivatives with potential antimalarial activity, neuropeptides S antagonists, N-substituted imidazoles, and other thio-containing compounds.
What are the CAS number and formula for 2-Piperidinoethyl isothiocyanate?
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The CAS number is 32813-24-4, and the empirical formula is C8H14N2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Piperidinoethyl isothiocyanate with an assay of 95%. This product is intended for research and chemical synthesis use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the primary safety concerns when handling 2-Piperidinoethyl isothiocyanate?
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This compound is classified as Dangerous. It is harmful if swallowed (H301), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used.
Is 2-Piperidinoethyl isothiocyanate shipped internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and 2-Piperidinoethyl isothiocyanate can be packed and exported accordingly.
How can I request a sample or obtain a quote for 2-Piperidinoethyl isothiocyanate?
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Please contact our sales team via the website or direct inquiry to request a sample or obtain a quotation for 2-Piperidinoethyl isothiocyanate.
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