2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt
2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt (CAS 321863-21-2) is a synthetic phospholipid commonly utilised in cell biology and lipid metabolism research. With a molecular weight of 783.99 and empirical formula C40H75NNaO10P, this compound forms negatively charged lipid bilayers. Its unique properties, including ion penetration characteristics, make it valuable for studying membrane dynamics and metabolic pathways. Tech Serve Solutions supplies this reagent for advanced research applications.
- IUPAC
- (2S,8R,18Z)- 2-Amino-5-hydroxy-10-oxo-8-[[(1-oxohexadecyl)oxy]methyl]-4,6,9-trioxa-5-phosphaheptacos-18-enoic acid 5-oxide monosodium salt,1-Hexadecanoyl-2-(cis-9-octadecenoyl)-sn-glycero-3-phospho-L-serine sodium salt,1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium salt,3-sn-Phosphatidyl-L-serine, 2-oleoyl-1-palmitoyl sodium salt,POPS-Na,PS(16:0/18:1(9Z)),PS(16:0/18:1)
- Synonyms
- 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium saltPOPS-NaPS(16:0/18:1(9Z))PS(16:0/18:1)3-sn-Phosphatidyl-L-serine, 2-oleoyl-1-palmitoyl sodium salt

Lipid Bilayer Formation
This phosphoserine derivative forms negatively charged lipid bilayers, crucial for modelling biological membranes. Molecular dynamics simulations highlight specific interactions of sodium ions with these bilayers, offering insights into membrane structure and permeability.
Cell Biology Research
As a component involved in glycerophospholipid metabolism, it serves as a research tool in cell biology. Its use aids in understanding complex cellular processes related to lipid signalling and membrane trafficking.
Metabolomics Studies
Within the field of metabolomics, this compound can be employed to study metabolic pathways involving phospholipids. Its specific structure and charge characteristics are relevant for analysing metabolic profiles and disruptions.
| Molecular weight | 783.99 |
|---|---|
| Empirical formula | C40H75NNaO10P |
| Assay | ≥75% (TLC) |
| Storage temperature | −20°C |
| Application | Forms negatively charged lipid bilayers. A molecular dynamics simulation indicates that Na+ ions penetrate unexpectedly far into the bilayer, well beyond the hydrophilic end groups.1 |
| Biological source | from synthetic |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt used for?
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This compound is primarily used in cell biology and lipid metabolism research for forming negatively charged lipid bilayers and studying associated metabolic pathways and metabolomics.
What is the CAS number and formula for 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt?
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The CAS number is 321863-21-2, and the empirical formula is C40H75NNaO10P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥75% (TLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for this product?
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When handling, it is essential to use safety measures including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK Germany classification of 3, indicating a high hazard to water.
How is 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt shipped and exported?
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This product is stored at -20°C. As a global supplier and exporter, Tech Serve Solutions adheres to all relevant regulations for shipping and exporting fine chemicals worldwide.
How can I request a quote or sample for this chemical?
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To request a quote or sample, please contact the Tech Serve Solutions sales department through our website or by phone. Our team will be pleased to assist you.
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