[D-Pro4, D-Trp7,9, Nle11]-Substance P Fragment 4-11
[D-Pro4, D-Trp7,9, Nle11]-Substance P Fragment 4-11 (CAS: 89430-34-2) is a synthetic peptide analogue of Substance P, with the empirical formula C58H77N13O10 and a molecular weight of 1116.31. This compound functions as a potent antagonist, primarily utilized in cell biology and neuroscience research for investigating tachykinin receptor pathways. Its specific sequence modification allows for detailed studies of receptor interactions and cellular signaling.
- IUPAC
- D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2
- Synonyms
- Nle11]-Substance P Fragment 4-1189430-34-2C58H77N13O10
![[D-Pro4, D-Trp7,9, Nle11]-Substance P Fragment 4-11 (C58H77N13O10) — chemical structure, CAS 89430-34-2; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F89430-34-2.png&w=3840&q=75)
Neuroscience Research
Used as a tool in neuroscience to study the roles of Substance P and tachykinins in pain transmission, inflammation, and other neurological processes. Its antagonist properties help delineate receptor-specific signaling pathways.
Cell Signaling Studies
Employed in cell biology to investigate G protein-coupled receptor (GPCR) signaling, particularly focusing on neurokinin receptors. It helps in understanding downstream cellular responses to tachykinin stimulation.
Peptide Receptor Binding Assays
Serves as a ligand in binding assays to characterize the affinity and specificity of neurokinin receptors. This aids in the development of novel therapeutic agents targeting these receptors.
Pharmacological Tool
Acts as a research-grade pharmacological agent for in vitro studies, providing a specific blockade of certain tachykinin receptor activities. It is not intended for human or veterinary use.
| Molecular weight | 1116.31 |
|---|---|
| Empirical formula | C58H77N13O10 |
| Assay | ≥95% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... TAC1(6863) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [D-Pro4, D-Trp7,9, Nle11]-Substance P Fragment 4-11 used for?
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[D-Pro4, D-Trp7,9, Nle11]-Substance P Fragment 4-11 is primarily used as an antagonist in cell biology and neuroscience research, particularly for studying tachykinin receptor pathways and cell signaling.
What are the CAS number and empirical formula?
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The CAS number is 89430-34-2, and the empirical formula is C58H77N13O10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥95% by HPLC. This product is intended for research use only and is not supplied as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling precautions?
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When handling this chemical, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is needed. The WGK Germany is 3, indicating a high hazard to water.
How is this product packed and shipped?
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This product is typically stored at -20°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team or use the online portal to request a sample or a quotation for [D-Pro4, D-Trp7,9, Nle11]-Substance P Fragment 4-11.
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