[D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH

CAS 68059-94-9D-Trp3Cell Biology

[D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH (CAS: 68059-94-9) is a synthetic peptide analogue of the Luteinizing Hormone-Releasing Hormone (LH-RH), with the empirical formula C67H84N16O13 and a molecular weight of 1321.48 g/mol. As a GnRH antagonist, it is primarily utilised in research settings for investigating cellular signalling pathways and reproductive endocrinology. This compound is supplied by TSS for laboratory use and research purposes.

Synonyms: 6]-LH-RH68059-94-9C67H84N16O13

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[D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH (D-Trp3) — chemical structure, CAS 68059-94-9; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyLH-RHPeptides and ProteinsPeptides for Cell BiologyReleasing Factors More...

01 /Applications

Reproductive Endocrinology Research

This LH-RH analogue serves as a valuable tool for studying the regulation of the hypothalamic-pituitary-gonadal axis. Researchers utilise it to investigate the complex mechanisms of hormone release and feedback loops.

Cellular Signalling Studies

The compound is employed in cell biology research to probe the signalling pathways activated by GnRH receptors. Its antagonistic properties allow for the dissection of downstream cellular events in response to receptor blockade.

Neuroscience Research Applications

Given the presence of GnRH receptors in the brain beyond the hypothalamus, this peptide is used to explore potential roles in neurobiological processes. Studies may focus on its influence on neuronal activity or behaviour.

02 /Properties

Molecular weight	1321.48
Empirical formula	C67H84N16O13
Assay	≥97% (HPLC)
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use
P308IF exposed or concerned

Protective equipment	Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	60
Safety statements (S)	53-22-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

68059-94-9

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is [D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH used for?

[D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH is primarily used in research settings, particularly within cell biology, cellular signalling, neuroscience, and reproductive endocrinology, to investigate the mechanisms of LH-RH and its receptor interactions.

What are the CAS number and formula for this compound?

The CAS number for [D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH is 68059-94-9, and its empirical formula is C67H84N16O13.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with an assay of ≥97% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should [D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH be handled?

This compound is classified as Danger (GHS08) and carries the hazard statement H360 (May damage fertility or the unborn child). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (e.g., N100 respirator), is essential during handling. Always consult the Safety Data Sheet (SDS) before use.

How is this chemical packed, shipped, and exported?

Products are carefully packed to ensure integrity during transit. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, facilitating international shipments.

How can I request a sample or quote for [D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH?

To request a sample or a quotation, please use the contact form on our website or contact our sales team directly, providing the product name and CAS number.