2,2′-Bis[(4S)-4-benzyl-2-oxazoline]
2,2′-Bis[(4S)-4-benzyl-2-oxazoline] (CAS: 133463-88-4), a chiral ligand with the molecular formula C20H20N2O2 and a molecular weight of 320.39 g/mol, is instrumental in asymmetric synthesis. It functions as a catalyst for the enantioselective hydrosilylation of ketones, contributing to stereoselective chemical transformations. This compound is supplied by Tech Serve Solutions for research and synthesis applications.
- IUPAC
- (S,S)-2,2′-Bis(4-benzyl-2-oxazoline),(S,S)-4,4′-Dibenzyl-2,2′-bi(2-oxazoline)
- Synonyms
- (S,S)-2,2′-Bis(4-benzyl-2-oxazoline)(S,S)-4,4′-Dibenzyl-2,2′-bi(2-oxazoline)
![2,2′-Bis[(4S)-4-benzyl-2-oxazoline] (C20H20N2O2) — chemical structure, CAS 133463-88-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F133463-88-4.png&w=3840&q=75)
Enantioselective Hydrosilylation Catalyst
This oxazoline derivative serves as a chiral catalyst for the enantioselective hydrosilylation of ketones. It facilitates the stereoselective reduction of carbonyl compounds, leading to chiral alcohols.
Chiral Ligand in Asymmetric Synthesis
As a privileged chiral ligand, it plays a key role in asymmetric synthesis. Its structure enables the induction of chirality in various organic transformations, crucial for the synthesis of enantiomerically pure compounds.
Reagent for Stereoselective Transformations
Used in chemical synthesis, this compound is valuable for developing stereoselective routes to complex molecules. Its application aids in controlling the stereochemical outcome of reactions.
| Molecular weight | 320.39 |
|---|---|
| Empirical formula | C20H20N2O2 |
| Assay | 98% |
| Optical activity | [α]20/D −40.6°, c = 1 in ethanol |
| Application | Catalyst for the enantioselective hydrosilylation of ketones.1 |
| Melting point | 129-132 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2′-Bis[(4S)-4-benzyl-2-oxazoline] used for?
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2,2′-Bis[(4S)-4-benzyl-2-oxazoline] is primarily used as a chiral catalyst for the enantioselective hydrosilylation of ketones in asymmetric synthesis.
What are the CAS number and chemical formula for 2,2′-Bis[(4S)-4-benzyl-2-oxazoline]?
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The CAS number for 2,2′-Bis[(4S)-4-benzyl-2-oxazoline] is 133463-88-4, and its empirical formula is C20H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2′-Bis[(4S)-4-benzyl-2-oxazoline] with an assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product documentation.
How should 2,2′-Bis[(4S)-4-benzyl-2-oxazoline] be handled safely?
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Handling requires a dust mask type N95 (US), eyeshields, and gloves. It is classified as a Warning, with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Ensure adequate ventilation.
Is this product available for export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals like 2,2′-Bis[(4S)-4-benzyl-2-oxazoline].
How can I request a sample or quote for 2,2′-Bis[(4S)-4-benzyl-2-oxazoline]?
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To request a sample or a quotation, please contact our sales department through the website or by calling us directly.
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