2-Nitrobenzyl bromide
2-Nitrobenzyl bromide (CAS 3958-60-9), with the molecular formula O2NC6H4CH2Br and a molar mass of 216.03 g/mol, is a key organic building block. This compound, also known as α-Bromo-2-nitrotoluene, serves as a valuable intermediate in various chemical syntheses. Its utility lies in its reactive benzylic bromide and nitro functional groups, facilitating diverse synthetic transformations in organic chemistry and material science research.
- IUPAC
- α-Bromo-2-nitrotoluene
- Synonyms
- α-Bromo-2-nitrotoluene
Organic Synthesis Intermediate
2-Nitrobenzyl bromide is frequently employed as a versatile intermediate in the synthesis of more complex organic molecules. Its reactivity allows for the introduction of the 2-nitrobenzyl group into various substrates via alkylation reactions.
Photolabile Protecting Groups
The 2-nitrobenzyl moiety can be used to construct photolabile protecting groups. Upon irradiation with UV light, these groups can be cleaved, releasing the protected functional group under mild conditions, which is advantageous in complex synthetic sequences.
Research and Development
As a readily available chemical building block, it is utilised in academic and industrial research laboratories for exploring new reaction pathways and developing novel chemical entities.
| Molecular weight | 216.03 |
|---|---|
| Linear formula | O2NC6H4CH2Br |
| Assay | ≥98.0% (GC) |
| Storage temperature | 2-8°C |
| Melting point | 44-46 °C(lit.)45-47 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Nitrobenzyl bromide used for?
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2-Nitrobenzyl bromide is primarily used as an intermediate in organic synthesis, particularly for introducing the 2-nitrobenzyl group and in the preparation of photolabile protecting groups.
What is the CAS number and chemical formula for 2-Nitrobenzyl bromide?
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The CAS number for 2-Nitrobenzyl bromide is 3958-60-9, and its chemical formula is O2NC6H4CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Nitrobenzyl bromide with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should 2-Nitrobenzyl bromide be handled safely?
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2-Nitrobenzyl bromide is classified as Danger (GHS05) with hazard statement H314 (Causes severe skin burns and eye damage). Handle with appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and respiratory protection. Ensure adequate ventilation.
Is 2-Nitrobenzyl bromide available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Nitrobenzyl bromide.
How can I request a quote or sample?
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Please contact our sales team through the website or by phone to request a quote or a sample of 2-Nitrobenzyl bromide.
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