2-Naphthylmagnesium bromide solution
2-Naphthylmagnesium bromide solution (CAS 21473-01-8), with a molecular weight of 231.37 g/mol, is an organometallic reagent. Supplied as a 0.5 M solution in THF, it is a valuable tool in organic synthesis. This Grignard reagent is primarily employed for introducing the 2-naphthyl group into organic molecules, facilitating the construction of complex structures in pharmaceutical and materials science research. Its reactivity demands careful handling due to its flammable and irritant nature.
Organic Synthesis
Serves as a key nucleophilic reagent for carbon-carbon bond formation. It is utilized in reactions such as alkylation, acylation, and addition to carbonyl compounds to introduce the 2-naphthyl moiety.
Pharmaceutical Intermediates
Enables the synthesis of advanced intermediates containing the naphthyl structure, which are often found in biologically active molecules and drug candidates.
Materials Science
Used in the preparation of novel organic materials, including polymers and organic light-emitting diodes (OLEDs), where the naphthyl group can influence electronic and optical properties.
| Molecular weight | 231.37 |
|---|---|
| Empirical formula | C10H7BrMg |
| Boiling point | 65 °C |
| Density | 0.951 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Naphthylmagnesium bromide solution used for?
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2-Naphthylmagnesium bromide solution (CAS 21473-01-8) is primarily used in organic synthesis for the introduction of the 2-naphthyl group into various organic molecules, serving as a key building block in the synthesis of pharmaceutical intermediates and advanced materials.
What are the CAS number and formula for 2-Naphthylmagnesium bromide solution?
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The CAS number for 2-Naphthylmagnesium bromide solution is 21473-01-8. The empirical formula (Hill notation) is C10H7BrMg.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Naphthylmagnesium bromide solution at a concentration of 0.5 M in THF. TSS does not represent this product as USP/BP/EP or any pharmacopoeia grade; it is suitable for research and technical applications.
What are the safety concerns when handling 2-Naphthylmagnesium bromide solution?
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This solution is highly flammable (H225) and can cause serious eye irritation (H319) and respiratory irritation (H335). It is suspected of causing cancer (H351) and may form explosive peroxides. Handle with extreme caution in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment.
How is 2-Naphthylmagnesium bromide solution packed, shipped, and exported?
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2-Naphthylmagnesium bromide solution is packed in accordance with UN 2924 regulations for flammable liquids with corrosive properties (PGII). TSS is an experienced global supplier and exporter, ensuring compliant and safe shipment.
How can I request a sample or quote for 2-Naphthylmagnesium bromide solution?
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To request a sample or a quote for 2-Naphthylmagnesium bromide solution, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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