2-Naphthyl trifluoromethanesulfonate
2-Naphthyl trifluoromethanesulfonate (CAS: 3857-83-8; Formula: CF3SO3C10H7; MW: 276.23) is a reactive organic compound. It serves as a valuable building block in organic synthesis, particularly in the preparation of diverse chemical structures. Its triflate group makes it useful for introducing the 2-naphthyl moiety into molecules via coupling reactions. This compound is essential for researchers and chemists involved in advanced chemical synthesis and the development of novel materials and pharmaceuticals.
- IUPAC
- 2-Naphthyl triflate

Organic Synthesis Reagent
2-Naphthyl trifluoromethanesulfonate functions as an effective electrophile in various coupling reactions, enabling the introduction of the 2-naphthyl group. This is crucial for constructing complex organic molecules and for structure-activity relationship studies in medicinal chemistry.
Building Block for Heterocycles
This triflate can be employed in the synthesis of complex heterocyclic frameworks. The reactivity of the triflate leaving group facilitates C-C bond formation, leading to the construction of intricate molecular architectures.
Intermediate in Pharmaceutical Research
As a versatile building block, it is utilized in the development pathways for potential pharmaceutical agents. Its application helps in exploring novel chemical entities with diverse biological activities.
| Molecular weight | 276.23 |
|---|---|
| Linear formula | CF3SO3C10H7 |
| Assay | 97% |
| Melting point | 30-32 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 22-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Naphthyl trifluoromethanesulfonate used for?
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2-Naphthyl trifluoromethanesulfonate is primarily used as a building block and reagent in organic synthesis, particularly for introducing the 2-naphthyl group into molecules through coupling reactions. It is also valuable in the synthesis of heterocyclic compounds and serves as an intermediate in pharmaceutical research.
What is the CAS number and chemical formula for 2-Naphthyl trifluoromethanesulfonate?
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The CAS number is 3857-83-8 and the chemical formula is CF3SO3C10H7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Naphthyl trifluoromethanesulfonate with a purity of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Naphthyl trifluoromethanesulfonate be handled safely?
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2-Naphthyl trifluoromethanesulfonate is classified as Danger with H314 hazard statement, indicating it causes severe skin burns and eye damage. It is imperative to use appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 respirators). Handling should be done in a well-ventilated area, following strict safety protocols.
How is 2-Naphthyl trifluoromethanesulfonate packed, shipped, and exported?
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2-Naphthyl trifluoromethanesulfonate is carefully packed according to international shipping regulations for hazardous materials (UN 3261, Class 8, Packing Group II). We ensure secure packaging for domestic and international export.
How can I request a sample or quote for 2-Naphthyl trifluoromethanesulfonate?
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To request a sample or a detailed quote, please contact our sales department through the 'Contact Us' section of our website, providing the product name and CAS number (3857-83-8).
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