2-Naphthylboronic acid
2-Naphthylboronic acid (CAS: 32316-92-0; Formula: C10H7B(OH)2; MW: 171.99) is a chemical reagent supplied by Tech Serve Solutions. This aryl boronic acid derivative serves as a valuable building block in organic synthesis. It is primarily utilised in palladium-catalyzed cross-coupling reactions and in the synthesis of complex organic molecules, including chiral alcohols and ketones.
- IUPAC
- 2-Naphthaleneboronic acid
- Synonyms
- 2-Naphthaleneboronic acid
Organic Synthesis
Used as a reactant in palladium-catalyzed reactions, such as Suzuki-Miyaura couplings, for the formation of carbon-carbon bonds. It is a key intermediate in the synthesis of biaryl compounds and other complex organic structures.
Chiral Alcohol Synthesis
Employed in enantioselective rhodium-catalyzed addition reactions to trifluoroacetophenones, yielding valuable chiral, tertiary trifluoromethyl alcohols.
Ketone and Heterocycle Synthesis
Facilitates palladium-catalyzed addition to nitriles, producing aryl ketones, and to aryloxy nitriles, leading to the formation of benzofurans.
| Molecular weight | 171.99 |
|---|---|
| Linear formula | C10H7B(OH)2 |
| Assay | ≥95.0% |
| Application | Used in a study of an enantioselective rhodium-catalyzed addition of aryl boronic acids to 2,2,2-trifluoroacetophenones leading to chiral, tertiary trifluoromethyl alcohols.1 Also employed in a study of a palladium-catalyzed addition of aryl boronic acids to nitriles providing aryl ketones and to aryloxy nitriles providing benzofurans.2 |
| Melting point | 269-275 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Naphthylboronic acid used for?
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2-Naphthylboronic acid is used in organic synthesis, particularly in palladium-catalyzed coupling reactions, for the preparation of chiral alcohols, aryl ketones, and benzofurans.
What is the CAS number and chemical formula for 2-Naphthylboronic acid?
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The CAS number is 32316-92-0 and the chemical formula is C10H7B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Naphthylboronic acid with a minimum assay of 95.0%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling precautions for 2-Naphthylboronic acid?
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2-Naphthylboronic acid is classified as a Warning substance (GHS07) with hazards H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
How is 2-Naphthylboronic acid shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all necessary regulations for safe and compliant shipping.
How can I request a sample or quote for 2-Naphthylboronic acid?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 2-Naphthylboronic acid.
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