2-(Methylthio)pyrazine
2-(Methylthio)pyrazine (CAS: 21948-70-9; C5H6N2S) is a heterocyclic organic compound with a molecular weight of 126.18 g/mol. This pyrazine derivative, also known as methyl pyrazinyl sulfide, serves as a valuable building block in chemical synthesis. Its unique structure makes it useful in the creation of more complex molecules, particularly within research and development settings for novel compound discovery.
- IUPAC
- Methyl pyrazinyl sulfide

Chemical Synthesis Intermediate
2-(Methylthio)pyrazine is employed as a key intermediate in the synthesis of various organic compounds. Its functional groups allow for diverse chemical transformations, facilitating the construction of complex molecular architectures.
Heterocyclic Chemistry Research
As a pyrazine derivative, this compound is of interest in heterocyclic chemistry research. It can be used to explore new reactions and develop novel heterocyclic systems with potential applications in medicinal chemistry and material science.
Building Block for Novel Compounds
This chemical acts as a versatile building block, enabling chemists to introduce the methylthio-pyrazine moiety into larger molecules. This is crucial for structure-activity relationship studies and the development of new chemical entities.
| Molecular weight | 126.18 |
|---|---|
| Empirical formula | C5H6N2S |
| Assay | 97% |
| Melting point | 44-47 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Methylthio)pyrazine used for?
+
2-(Methylthio)pyrazine is primarily used as a building block and intermediate in chemical synthesis and heterocyclic chemistry research.
What is the CAS number and formula for 2-(Methylthio)pyrazine?
+
The CAS number is 21948-70-9 and the empirical formula is C5H6N2S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-(Methylthio)pyrazine with an assay of 97%. This is a technical/research grade material and TSS does not represent it as USP, BP, or EP grade.
How should 2-(Methylthio)pyrazine be handled?
+
Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray. Ensure adequate ventilation. Refer to the Safety Data Sheet for full handling instructions.
What are the primary hazards associated with 2-(Methylthio)pyrazine?
+
2-(Methylthio)pyrazine is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335).
How is 2-(Methylthio)pyrazine packed, shipped, and exported?
+
Tech Serve Solutions specialises in the global supply and export of fine chemicals. Specific packing details are available upon request, and we adhere to all relevant shipping regulations for hazardous materials.
How can I request a sample or a quote for 2-(Methylthio)pyrazine?
+
To request a sample or a quote, please contact our sales team directly through our website or by phone, providing the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis