2-(Methylthio)phenylboronic acid
2-(Methylthio)phenylboronic acid (CAS: 168618-42-6; Formula: CH3SC6H4B(OH)2; MW: 168.02) is a valuable organoboronic acid derivative. It functions as a key reactant in sophisticated organic synthesis, particularly for palladium-catalyzed cross-coupling reactions. Its specific substitution pattern makes it a useful building block for creating complex molecules in pharmaceutical research and materials science.
- IUPAC
- 2-(Methylthio)benzeneboronic acid,2-Methylsulfanylphenylboronic acid
- Synonyms
- 2-(Methylthio)benzeneboronic acid2-Methylsulfanylphenylboronic acid
Palladium-Catalyzed Cross-Coupling Reactions
This boronic acid serves as a crucial coupling partner in palladium-catalyzed cross-coupling reactions. These reactions are fundamental in modern organic synthesis for forming carbon-carbon bonds with high efficiency and selectivity.
Suzuki-Miyaura Coupling
It is particularly well-suited for Suzuki-Miyaura coupling reactions. This application allows for the introduction of the 2-(methylthio)phenyl group into various organic frameworks, facilitating the synthesis of complex organic molecules.
Organic Synthesis Building Block
As a monosubstituted aryl boronic acid, it acts as a versatile building block in general organic synthesis. Its structure enables the construction of diverse molecular architectures for research and development purposes.
| Molecular weight | 168.02 |
|---|---|
| Linear formula | CH3SC6H4B(OH)2 |
| Application | Reactant for:• Palladium-catalyzed cross-coupling reactions1• Suzuki-Miyaura coupling reactions2 |
| Melting point | 77-83 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Methylthio)phenylboronic acid primarily used for?
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2-(Methylthio)phenylboronic acid is primarily used as a reactant in palladium-catalyzed cross-coupling reactions, most notably the Suzuki-Miyaura coupling, to synthesise complex organic molecules.
What are the CAS number and chemical formula for 2-(Methylthio)phenylboronic acid?
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The CAS number is 168618-42-6, and the chemical formula is CH3SC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply for 2-(Methylthio)phenylboronic acid?
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Tech Serve Solutions supplies this compound typically as a research or technical grade. The exact purity is detailed on the Certificate of Analysis provided with each batch. We do not represent it as USP, BP, or EP grade.
What are the safety considerations when handling 2-(Methylthio)phenylboronic acid?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if airborne exposure is possible. Consult the Safety Data Sheet for full hazard information.
How is 2-(Methylthio)phenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions ensures appropriate packaging for safe transport, adhering to international shipping regulations. We are experienced in exporting chemicals globally to research institutions and industrial clients.
How can I request a sample or quote for 2-(Methylthio)phenylboronic acid?
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To request a sample or a quotation, please contact our sales team through the website or direct email, providing your specific requirements and delivery details.
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