2-Methoxyethoxymethyl chloride
2-Methoxyethoxymethyl chloride (CAS: 3970-21-6, Formula: CH3OCH2CH2OCH2Cl) is a chemical reagent with a molecular weight of 124.57 g/mol. It is primarily utilised as an effective hydroxyl-protecting agent. The MEM (Methoxyethoxymethyl) ethers it forms are stable under a variety of reaction conditions and can be selectively cleaved, making it valuable in complex organic synthesis.
- IUPAC
- β-Methoxyethoxymethyl chloride,MEM-chloride
- Synonyms
- β-Methoxyethoxymethyl chloride, MEM-chloride
Hydroxyl Protection
Serves as a key reagent for the protection of hydroxyl groups in organic synthesis. The resulting MEM ethers exhibit stability towards diverse reaction conditions.
Selective Deprotection
The MEM protecting group can be selectively removed under specific aprotic conditions, allowing for precise manipulation in multi-step syntheses without affecting other functional groups.
Organic Synthesis
A valuable tool in general organic synthesis, enabling chemists to control reactivity and achieve targeted molecular transformations.
| Molecular weight | 124.57 |
|---|---|
| Linear formula | CH3OCH2CH2OCH2Cl |
| Boiling point | 50-52 °C/13 mmHg(lit.) |
| Density | 1.091 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.427(lit.) |
| Storage temperature | 2-8°C |
| Application | OH-protecting reagent. MEM ethers are stable to a variety of reaction conditions and are selectively cleaved under aprotic conditions in the presence of a wide rangeof OH-protected moieties.1,2 |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 54 °C / 129.2 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-10-20/22-36/37/38 |
| Safety statements (S) | 53-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxyethoxymethyl chloride used for?
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2-Methoxyethoxymethyl chloride is primarily used as a hydroxyl-protecting reagent in organic synthesis. The MEM ethers formed are stable to various reaction conditions and can be selectively cleaved.
What are the CAS number and formula for 2-Methoxyethoxymethyl chloride?
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The CAS number is 3970-21-6 and the chemical formula is CH3OCH2CH2OCH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxyethoxymethyl chloride meeting specified technical or research grades. The exact assay and purity details are available upon request, and TSS does not represent this product as USP/BP/EP grade.
How should 2-Methoxyethoxymethyl chloride be handled safely?
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2-Methoxyethoxymethyl chloride is a dangerous substance. It is flammable (H226), harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), may cause respiratory irritation (H335), and may cause cancer (H350). Always use with adequate ventilation, wear appropriate personal protective equipment including eyeshields, face shields, gloves, and a suitable respirator. Store at 2-8°C.
Is 2-Methoxyethoxymethyl chloride flammable?
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Yes, 2-Methoxyethoxymethyl chloride is flammable, with a flash point of 54°C (129.2°F) and is classified under hazard statement H226.
How is 2-Methoxyethoxymethyl chloride shipped and exported?
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2-Methoxyethoxymethyl chloride is classified as UN 2810, Hazard Class 6.1, Packing Group II. Tech Serve Solutions, as a specialist global supplier and exporter, handles its packaging and shipping in accordance with all relevant international regulations.
How can I request a quote or sample?
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To request a quote or a sample of 2-Methoxyethoxymethyl chloride, please contact our sales department through the website or by phone.
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