2-Methoxyethyl chloroformate
2-Methoxyethyl chloroformate (CAS 628-12-6), molecular formula CH3OCH2CH2OCOCl, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- (2-Methoxyethoxy)carbonyl chloride,(Chloro)(2-methoxyethoxy)methanone,2-Methoxyethyl carbonochloridate,Chloroformic acid 2-methoxyethyl ester

| Molecular weight | 138.55 |
|---|---|
| Linear formula | CH3OCH2CH2OCOCl |
| Boiling point | 157-158 °C(lit.) |
| Density | 1.192 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4200(lit.) |
| Storage temperature | 2-8°C |
| Application | Reactant for:• Preparation of N-bridged bicyclic sulfonamides as inhibitors of γ-secretase1• Preparation of dimethoxyethyl azodicarboxylate via amidation/oxidation and application to Mitsunobu reaction2• Regioselective, stereoselective, and kinetically-controlled nickel-catalyzed cyanoesterification of allenes chloroformates and TMSCN3• Preparation of amino carboxamidobenzothiazoles as Lck inhibitors4• Preparation of nonracemic spirooxindoles using a stereoselective three-component coupling reaction as the key step and using acylation reactions to add structural diversity5 |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxyethyl chloroformate?
+
2-Methoxyethyl chloroformate (CAS 628-12-6), molecular formula CH3OCH2CH2OCOCl, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of 2-Methoxyethyl chloroformate does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxyethyl chloroformate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of 2-Methoxyethyl chloroformate?
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2-Methoxyethyl chloroformate has CAS number 628-12-6 and molecular formula CH3OCH2CH2OCOCl. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for 2-Methoxyethyl chloroformate?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of 2-Methoxyethyl chloroformate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should 2-Methoxyethyl chloroformate be stored?
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Store 2-Methoxyethyl chloroformate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is 2-Methoxyethyl chloroformate used for?
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2-Methoxyethyl chloroformate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for 2-Methoxyethyl chloroformate?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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