2-Methoxy-5-trifluoromethylphenylboronic acid
2-Methoxy-5-trifluoromethylphenylboronic acid (CAS: 240139-82-6; Formula: C8H8BF3O3; MW: 219.95) is a disubstituted aryl boronic acid derivative. It serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its unique trifluoromethyl and methoxy substituents make it useful for introducing specific structural motifs in the development of complex molecules for pharmaceutical and materials science research.

Suzuki-Miyaura Cross-Coupling Reagent
This boronic acid is employed as a coupling partner in Suzuki-Miyaura reactions, facilitating the formation of carbon-carbon bonds. It is used to synthesise biaryl compounds and other complex organic structures.
Organic Synthesis Intermediate
It functions as a key intermediate in multi-step syntheses for the creation of novel organic molecules. The trifluoromethyl group imparts distinct electronic and lipophilic properties to target compounds.
Pharmaceutical Research and Development
Used in the discovery and development of new pharmaceutical agents. Its structure can be incorporated into potential drug candidates to modulate their biological activity and pharmacokinetic profiles.
Materials Science
Applied in the synthesis of advanced materials, such as organic semiconductors and functional polymers, where the trifluoromethylphenyl moiety can influence electronic or optical properties.
| Molecular weight | 219.95 |
|---|---|
| Empirical formula | C8H8BF3O3 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxy-5-trifluoromethylphenylboronic acid used for?
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2-Methoxy-5-trifluoromethylphenylboronic acid is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in the research and development of pharmaceuticals and advanced materials.
What is the CAS number and formula for 2-Methoxy-5-trifluoromethylphenylboronic acid?
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The CAS number is 240139-82-6 and the molecular formula is C8H8BF3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research or technical grade chemical. We do not represent it as USP, BP, EP, or pharmacopoeia grade.
How should 2-Methoxy-5-trifluoromethylphenylboronic acid be handled?
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Refer to the Safety Data Sheet (SDS) for detailed safety and handling information. General precautions for handling fine chemicals should be observed, including avoiding contact with skin and eyes and ensuring adequate ventilation.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team via the website or phone to request a quote or sample for 2-Methoxy-5-trifluoromethylphenylboronic acid.
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