2-Iodo-5-methylthiophene
2-Iodo-5-methylthiophene (CAS: 16494-36-3), with the molecular formula C5H5IS and a molar mass of 224.06 g/mol, is a halogenated heterocyclic compound. This thiophene derivative serves as a valuable building block in organic synthesis. Its structure, featuring an iodine atom and a methyl group on the thiophene ring, allows for diverse chemical transformations, making it useful in the development of complex molecules for research and development.

Organic Synthesis Intermediate
2-Iodo-5-methylthiophene is employed as a key intermediate in the synthesis of various organic compounds. The iodine substituent facilitates cross-coupling reactions, enabling the construction of carbon-carbon bonds.
Heterocyclic Chemistry Research
As a substituted thiophene, this compound is utilized in academic and industrial research focused on heterocyclic chemistry. It aids in the exploration of novel thiophene-based structures and their properties.
Building Block for Fine Chemicals
This chemical acts as a foundational building block for the creation of more complex fine chemicals and potential pharmaceutical intermediates, leveraging its reactive iodine atom and thiophene core.
| Molecular weight | 224.06 |
|---|---|
| Empirical formula | C5H5IS |
| Assay | 97% |
| Boiling point | 81-83 °C/10 mmHg(lit.) |
| Density | 1.852 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.626(lit.) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Iodo-5-methylthiophene primarily used for?
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2-Iodo-5-methylthiophene (CAS: 16494-36-3) is primarily used as a building block and intermediate in organic synthesis, particularly in heterocyclic chemistry research and the development of fine chemicals.
What are the CAS number and molecular formula of 2-Iodo-5-methylthiophene?
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The CAS number for 2-Iodo-5-methylthiophene is 16494-36-3, and its molecular formula is C5H5IS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Iodo-5-methylthiophene with a purity of 97%. This is a technical/research grade product, and TSS does not represent it as USP, BP, or EP grade.
How should 2-Iodo-5-methylthiophene be handled and stored?
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Handling 2-Iodo-5-methylthiophene requires appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection. It should be stored at refrigeration temperatures between 2-8°C to maintain its integrity.
Is 2-Iodo-5-methylthiophene a regulated or controlled substance?
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Based on the provided data, 2-Iodo-5-methylthiophene is classified under NA 1993 / PGIII for transport, indicating it is a flammable liquid, but it is not listed as a controlled or scheduled substance.
How can I request a sample or a quote for 2-Iodo-5-methylthiophene?
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To request a sample or obtain a quote for 2-Iodo-5-methylthiophene, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
How is 2-Iodo-5-methylthiophene packed and exported?
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2-Iodo-5-methylthiophene is carefully packed according to transport regulations (NA 1993 / PGIII) and is available for export globally by Tech Serve Solutions.
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