2-Iodo-5-nitropyridine
2-Iodo-5-nitropyridine (CAS: 28080-54-8), a key heterocyclic compound with the molecular formula C5H3IN2O2 and a molecular weight of 249.99 g/mol, serves as a valuable building block in organic synthesis. Its structure, featuring both an iodine atom and a nitro group on a pyridine ring, enables diverse chemical transformations. This compound is primarily utilised in the development of more complex molecules for research and specialised chemical applications, particularly within the pharmaceutical and materials science sectors.
Organic Synthesis Intermediate
2-Iodo-5-nitropyridine is a versatile intermediate for constructing complex organic molecules. The iodine atom allows for various coupling reactions, such as Suzuki and Sonogashira couplings, to introduce new carbon-carbon bonds. The nitro group can be reduced to an amine, opening pathways to further functionalisation.
Pharmaceutical Research
This compound acts as a crucial building block in the synthesis of potential pharmaceutical agents. Its pyridine core is present in many biologically active molecules, and the strategically placed iodine and nitro groups facilitate the introduction of pharmacologically relevant substituents.
Materials Science
The unique electronic properties conferred by the nitro group and the potential for further modification make 2-Iodo-5-nitropyridine a useful component in the design and synthesis of novel materials, including organic electronics and specialised polymers.
| Molecular weight | 249.99 |
|---|---|
| Empirical formula | C5H3IN2O2 |
| Assay | 97% |
| Melting point | 163-168 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Iodo-5-nitropyridine used for?
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2-Iodo-5-nitropyridine is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and materials science for creating more complex molecules.
What is the CAS number and formula for 2-Iodo-5-nitropyridine?
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The CAS number is 28080-54-8, and its molecular formula is C5H3IN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Iodo-5-nitropyridine with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main hazards associated with 2-Iodo-5-nitropyridine?
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This compound is classified as Danger, with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H317 (May cause an allergic skin reaction), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including dust masks, eyeshields, faceshields, and gloves, should be worn when handling.
How is 2-Iodo-5-nitropyridine packed and shipped?
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2-Iodo-5-nitropyridine is carefully packed to ensure integrity during transport and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample for 2-Iodo-5-nitropyridine?
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To request a quote or sample of 2-Iodo-5-nitropyridine, please use the contact form on our website or reach out to our sales department directly.
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