2-Hydroxypyridine
2-Hydroxypyridine (CAS: 142-08-5; Formula: C5H5NO) is a heterocyclic organic compound with a molecular weight of 95.10 g/mol. It is known for its tautomeric equilibrium with 2-pyridone, influencing its reactivity. This versatile compound serves as a crucial building block in organic synthesis, particularly in the preparation of more complex pyridine derivatives and related heterocycles for various chemical research and development applications.
- IUPAC
- 2(1H)-Pyridone,2-Pyridinol
- Synonyms
- 2-Pyridinol2(1H)-Pyridone2-Hydroxypyridin

Organic Synthesis Intermediate
2-Hydroxypyridine acts as a valuable synthon in the construction of diverse organic molecules. Its reactive sites allow for numerous transformations, making it indispensable in multi-step synthetic pathways.
Heterocyclic Chemistry
As a substituted pyridine, it is frequently employed in the synthesis of novel heterocyclic compounds. These derivatives often possess interesting biological or material properties, driving research in medicinal chemistry and materials science.
Research and Development
This chemical is utilized in academic and industrial research laboratories for exploring new reaction methodologies and developing novel compounds. Its established chemistry makes it a reliable reagent for exploratory synthesis.
| Molecular weight | 95.10 |
|---|---|
| Empirical formula | C5H5NO |
| Assay | 97% |
| Boiling point | 280-281 °C(lit.) |
| Melting point | 105-107 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Hydroxypyridine used for?
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2-Hydroxypyridine is primarily used as a building block in organic synthesis and for the preparation of various heterocyclic compounds, particularly in research and development settings.
What is the CAS number and formula for 2-Hydroxypyridine?
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The CAS number for 2-Hydroxypyridine is 142-08-5, and its chemical formula is C5H5NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Hydroxypyridine with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should 2-Hydroxypyridine be handled safely?
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2-Hydroxypyridine is classified as toxic if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Always handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, in a well-ventilated area. Refer to the safety data sheet for detailed handling information.
Is 2-Hydroxypyridine a controlled substance?
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Based on the provided data, 2-Hydroxypyridine is not indicated as a controlled substance. However, regulations can vary by jurisdiction.
How is 2-Hydroxypyridine typically packed and exported?
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2-Hydroxypyridine is packed and shipped according to UN 2811 6.1 / PGIII regulations for hazardous materials. TSS is a global supplier and exporter experienced in international shipping protocols.
How can I request a sample or quote for 2-Hydroxypyridine?
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To request a sample or a quote for 2-Hydroxypyridine, please contact our sales department through the website or by phone, providing your specific requirements.
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