[Hydroxy(tosyloxy)iodo]benzene
[Hydroxy(tosyloxy)iodo]benzene (CAS: 27126-76-7), with the formula CH3C6H4SO3I(OH)C6H5 and a molecular weight of 392.21, is a hypervalent iodine compound widely employed as an oxidant. Its utility is primarily in organic synthesis, facilitating the formation of various carbon-carbon and carbon-heteroatom bonds. This reagent offers a selective and efficient method for oxidation reactions in the preparation of complex molecules.
- IUPAC
- HTIB,Hydroxy(4-methylbenzenesulfonato-O)phenyliodine,Hydroxy(phenyl)iodo tosylate,Iodosobenzene-I-mono-p-toluenesulfonate,Koser’s reagent,NSC 294176,Phenyliodosyl hydroxide tosylate,[Hydroxy(4-toluenesulfonato)iodo]benzene
- Synonyms
- HTIBHydroxy(4-methylbenzenesulfonato-O)phenyliodineHydroxy(phenyl)iodo tosylateIodosobenzene-I-mono-p-toluenesulfonateKoser’s reagentNSC 294176Phenyliodosyl hydroxide tosylate[Hydroxy(4-toluenesulfonato)iodo]benzene
![[Hydroxy(tosyloxy)iodo]benzene (CH3C6H4SO3I(OH)C6H5) — chemical structure, CAS 27126-76-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F27126-76-7.png&w=3840&q=75)
Oxidant in Organic Synthesis
Serves as a key oxidant for a range of organic transformations, enabling the synthesis of diverse chemical entities. It is particularly useful for introducing oxygen functionalities and facilitating coupling reactions in complex molecular architectures.
Preparation of Heterocyclic Compounds
Used in the synthesis of various heterocyclic systems, which are crucial building blocks in pharmaceuticals and agrochemicals. Its ability to act as an electrophilic iodine source promotes cyclization reactions.
Oxidative Cyclization Reactions
Facilitates oxidative cyclization reactions, leading to the formation of cyclic ethers, amines, and other heterocycles. This reagent provides a valuable tool for constructing fused and spirocyclic systems.
| Molecular weight | 392.21 |
|---|---|
| Linear formula | CH3C6H4SO3I(OH)C6H5 |
| Assay | ≥97.0% (AT) |
| Application | Widely used oxidant in the synthesis of various organic compounds.9 |
| Melting point | 131-137 °C(lit.)131-137 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [Hydroxy(tosyloxy)iodo]benzene used for?
+
[Hydroxy(tosyloxy)iodo]benzene (CAS: 27126-76-7) is primarily utilised as an effective oxidant in various organic synthesis pathways, particularly in the preparation of diverse organic compounds and heterocyclic systems.
What is the CAS number and formula for [Hydroxy(tosyloxy)iodo]benzene?
+
The CAS number for [Hydroxy(tosyloxy)iodo]benzene is 27126-76-7, and its molecular formula is CH3C6H4SO3I(OH)C6H5.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies [Hydroxy(tosyloxy)iodo]benzene with an assay of ≥97.0% (AT). We do not represent this product as USP, BP, or EP grade, and it is suitable for laboratory and research applications.
How should [Hydroxy(tosyloxy)iodo]benzene be handled?
+
As a Warning substance, [Hydroxy(tosyloxy)iodo]benzene can cause skin irritation (H315) and serious eye irritation (H319). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid dust formation. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do so. Continue rinsing.
Is [Hydroxy(tosyloxy)iodo]benzene suitable for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including [Hydroxy(tosyloxy)iodo]benzene, adhering to international shipping regulations.
How can I request a quote or sample for [Hydroxy(tosyloxy)iodo]benzene?
+
To request a quote or sample of [Hydroxy(tosyloxy)iodo]benzene, please contact our sales team through the website or by phone. Provide your contact details and the quantity required.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis