2′-Fluoro-4′-methoxyacetophenone
2′-Fluoro-4′-methoxyacetophenone (CAS: 74457-86-6) is a fluorinated organic building block with the molecular formula C9H9FO2 and a molecular weight of 168.16 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. Its specific substitution pattern makes it a useful starting material for introducing fluorinated aryl moieties into more complex molecular structures.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the incorporation of a fluorinated aromatic ring is desired for modulating pharmacokinetic properties or biological activity.
Agrochemical Development
Serves as a key building block in the research and development of new pesticides and herbicides, contributing to the creation of compounds with enhanced efficacy and targeted action.
Materials Science Research
Can be employed in the synthesis of specialty polymers or functional materials where fluorine incorporation influences properties such as thermal stability or refractive index.
Organic Synthesis Reagent
A versatile reagent for academic and industrial research laboratories engaged in the discovery of new chemical entities and synthetic methodologies.
| Molecular weight | 168.16 |
|---|---|
| Linear formula | FC6H3(OCH3)COCH3 |
| Assay | 99% |
| Melting point | 52-54 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Fluoro-4′-methoxyacetophenone used for?
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2′-Fluoro-4′-methoxyacetophenone is primarily used as an intermediate in organic synthesis for pharmaceuticals, agrochemicals, and materials science research.
What are the CAS number and chemical formula for this compound?
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The CAS number is 74457-86-6 and the linear formula is C9H9FO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Fluoro-4′-methoxyacetophenone with an assay of 99%. It is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 2′-Fluoro-4′-methoxyacetophenone be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Avoid inhalation of dust, eye contact, and skin contact. Ensure good ventilation. Refer to the Safety Data Sheet for comprehensive guidance.
Is this product suitable for export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including 2′-Fluoro-4′-methoxyacetophenone.
How can I request a quote or sample?
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Please contact our sales department via the website or your usual sales representative to request a quote or a sample of 2′-Fluoro-4′-methoxyacetophenone.
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