2′-Fluoroacetophenone
2′-Fluoroacetophenone (CAS: 445-27-2) is a fluorinated ketone with the molecular formula C8H7FO and a molecular weight of 138.14 g/mol. This organic compound serves as a valuable building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its structure, featuring both a ketone and an aromatic fluorine atom, allows for diverse chemical transformations and incorporation into complex molecules.
Pharmaceutical Intermediate
2′-Fluoroacetophenone is utilized in the synthesis of various active pharmaceutical ingredients (APIs). The presence of the fluorine atom can influence pharmacokinetic properties such as metabolic stability and lipophilicity, making it an attractive moiety in drug design.
Agrochemical Synthesis
This compound finds application as a precursor in the development of novel agrochemicals. Its unique structural features can contribute to the efficacy and targeted action of pesticides and herbicides.
Organic Synthesis Reagent
As a versatile building block, 2′-Fluoroacetophenone enables chemists to introduce the 2-fluoroacetylphenyl group into various organic structures. It is employed in reactions to create more complex fluorinated organic molecules for research and development.
| Molecular weight | 138.14 |
|---|---|
| Linear formula | FC6H4COCH3 |
| Assay | 97% |
| Grade | purum |
| Boiling point | 187-189 °C(lit.) |
| Density | 1.137 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.507(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Fluoroacetophenone used for?
+
2′-Fluoroacetophenone is primarily used as an intermediate and building block in the synthesis of pharmaceuticals and agrochemicals, as well as in general organic synthesis for creating complex fluorinated molecules.
What is the CAS number and chemical formula for 2′-Fluoroacetophenone?
+
The CAS number for 2′-Fluoroacetophenone is 445-27-2, and its linear chemical formula is C8H7FO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2′-Fluoroacetophenone with a minimum purity of 97% (purum grade). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2′-Fluoroacetophenone be handled safely?
+
2′-Fluoroacetophenone is classified as a warning substance, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including safety goggles, gloves, and ensure adequate ventilation or use a suitable respirator. Avoid breathing dust/fume/gas/mist/vapours/spray.
Is 2′-Fluoroacetophenone a controlled substance?
+
Based on the provided data, there is no indication that 2′-Fluoroacetophenone (CAS: 445-27-2) is a controlled substance.
How is 2′-Fluoroacetophenone packed and shipped?
+
Tech Serve Solutions offers 2′-Fluoroacetophenone for export globally. Packaging and shipping adhere to international regulations for chemical transport, with details available upon request. The product has a flash point of 62 °C (143.6 °F) and is shipped under UN 1993 / PGIII.
How can I request a quote or sample for 2′-Fluoroacetophenone?
+
To request a quote or a sample of 2′-Fluoroacetophenone, please contact our sales team through our website or by phone. We are happy to assist with your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis