2′-Fluoro-6′-(trifluoromethyl)acetophenone
2′-Fluoro-6′-(trifluoromethyl)acetophenone (CAS: 174013-29-7) is a fluorinated organic building block with the linear formula FC₆H₃(CF₃)COCH₃ and a molecular weight of 206.14 g/mol. This ketone serves as a valuable intermediate in organic synthesis, particularly for introducing fluorinated aryl moieties into more complex molecules. It is commonly employed in research and development settings within the pharmaceutical and agrochemical industries.
Pharmaceutical Synthesis
Utilised as a key intermediate in the development of novel pharmaceutical compounds. Its unique fluorinated structure can influence drug metabolism and binding affinity.
Agrochemical Development
Serves as a building block for the synthesis of advanced agrochemicals. The trifluoromethyl and fluoro substituents can enhance biological activity and stability.
Materials Science Research
Involved in the creation of specialised organic materials where fluorination imparts desirable properties such as thermal stability or altered electronic characteristics.
Organic Synthesis Reagent
A versatile reagent for organic chemists undertaking complex molecular constructions, enabling the introduction of specific functional groups.
| Molecular weight | 206.14 |
|---|---|
| Linear formula | FC6H3(CF3)COCH3 |
| Assay | 98% |
| Density | 1.326 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.439(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Fluoro-6′-(trifluoromethyl)acetophenone used for?
+
2′-Fluoro-6′-(trifluoromethyl)acetophenone is used as a key intermediate and building block in organic synthesis, particularly for pharmaceuticals, agrochemicals, and advanced materials research.
What is the CAS number and chemical formula for 2′-Fluoro-6′-(trifluoromethyl)acetophenone?
+
The CAS number is 174013-29-7, and the linear formula is FC₆H₃(CF₃)COCH₃.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound with a minimum assay of 98%. It is typically considered a technical or research grade material and is not represented as USP, BP, or EP.
How should 2′-Fluoro-6′-(trifluoromethyl)acetophenone be handled safely?
+
This compound is a warning agent (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be worn, and handling should occur in a well-ventilated area or fume hood.
Is this chemical packed and shipped internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, fulfilling international orders.
How can I request a sample or quote?
+
To request a sample or a quote, please use the contact form on our website or contact our sales department directly.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis