2-(Difluoromethoxy)aniline
2-(Difluoromethoxy)aniline (CAS 22236-04-0) is an organic compound with the linear formula F₂CHOC₆H₄NH₂. It has a molecular weight of 159.13 g/mol. This fluorinated aniline derivative serves as a valuable building block in organic synthesis, particularly for introducing the difluoromethoxy moiety into complex molecules. Its applications are primarily within chemical research and development, contributing to the synthesis of novel compounds.
Organic Synthesis Intermediate
This compound is utilised as a key intermediate in multi-step organic syntheses. Its difluoromethoxy group offers unique electronic and lipophilic properties, making it desirable for constructing advanced chemical structures.
Fluorinated Building Block
As a source of the difluoromethoxy group, 2-(Difluoromethoxy)aniline is employed in the development of new molecules, especially in fields requiring fluorinated organic compounds, such as pharmaceuticals and agrochemicals.
Research and Development
It is used in academic and industrial research laboratories for exploring new chemical pathways and synthesising novel materials. Its specific functional groups enable diverse chemical transformations.
| Molecular weight | 159.13 |
|---|---|
| Linear formula | F2CHOC6H4NH2 |
| Assay | 97% |
| Boiling point | 205 °C(lit.) |
| Density | 1.272 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.505(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Difluoromethoxy)aniline used for?
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2-(Difluoromethoxy)aniline is primarily used as a building block in organic synthesis and for chemical research and development, enabling the introduction of the difluoromethoxy group into various molecules.
What is the CAS number and formula for 2-(Difluoromethoxy)aniline?
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The CAS number for 2-(Difluoromethoxy)aniline is 22236-04-0, and its linear formula is F₂CHOC₆H₄NH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Difluoromethoxy)aniline with a minimum assay of 97%. This product is suitable for research and chemical synthesis and is not represented as USP, BP, or EP grade.
How should 2-(Difluoromethoxy)aniline be handled safely?
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2-(Difluoromethoxy)aniline is a Warning substance (GHS07) and is harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be used during handling. Refer to the safety data sheet for comprehensive handling instructions.
Is 2-(Difluoromethoxy)aniline available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-(Difluoromethoxy)aniline, and can facilitate international shipments.
How can I request a quote or sample?
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To request a quote or sample of 2-(Difluoromethoxy)aniline, please contact our sales department via the website or by phone, providing your specific requirements.
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