2-(Difluoromethyl)pyridine
2-(Difluoromethyl)pyridine (CAS 114468-01-8), with the molecular formula C6H5F2N and a molecular weight of 129.11 g/mol, is a valuable fluorinated heterocyclic building block. This compound serves as a key intermediate in organic synthesis, particularly for the introduction of the difluoromethyl group into complex molecules. Its chemical structure makes it useful in the development of novel pharmaceuticals and agrochemicals.
Organic Synthesis Intermediate
2-(Difluoromethyl)pyridine is employed as a versatile building block in the synthesis of more complex organic molecules. It is particularly useful for incorporating the difluoromethyl moiety, which can significantly alter the physicochemical and biological properties of target compounds.
Pharmaceutical Research and Development
This compound finds application in the R&D of new pharmaceutical agents. The difluoromethyl group is known to enhance metabolic stability and lipophilicity, properties often desirable in drug candidates.
Agrochemical Synthesis
It serves as a precursor in the development of novel agrochemicals, including herbicides, insecticides, and fungicides. The fluorine atoms can influence the efficacy and environmental persistence of these agents.
| Molecular weight | 129.11 |
|---|---|
| Empirical formula | C6H5F2N |
| Assay | 97%97% |
| Density | 1.204 g/mL at 25 °C |
| Solubility | : soluble1.454 at 20 °C |
Hazard statements
- H226Flammable liquid and vapour
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 41 °C / 105.8 °F |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Difluoromethyl)pyridine used for?
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2-(Difluoromethyl)pyridine (CAS 114468-01-8) is used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, owing to its difluoromethyl group.
What are the CAS number and formula for 2-(Difluoromethyl)pyridine?
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The CAS number for 2-(Difluoromethyl)pyridine is 114468-01-8, and its empirical formula is C6H5F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Difluoromethyl)pyridine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-(Difluoromethyl)pyridine be handled safely?
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2-(Difluoromethyl)pyridine is a flammable liquid and vapour (H226) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is 2-(Difluoromethyl)pyridine available for export?
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Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals, including 2-(Difluoromethyl)pyridine.
How can I request a sample or quote?
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Please contact our sales department via the website or provide your details through the 'Request a Quote' or 'Request a Sample' forms to receive prompt assistance.
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