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2-Deoxy-D-glucose

CAS 154-17-6C6H12O5Biochemicals & Reagents

2-Deoxy-D-glucose (CAS: 154-17-6, Formula: C6H12O5) is a glucose analogue with a molecular weight of 164.16 g/mol. This biochemical compound functions as a potent inhibitor of glucose metabolism. Its primary utility lies in research settings, particularly in studies related to cellular energy pathways, cancer research, and as a tool in glycobiology and molecular biology for investigating carbohydrate-related processes.

IUPAC
2-Deoxy-D-arabinohexose,2-Deoxyglucose
Synonyms
2-Deoxy-D-arabinohexose2-Deoxyglucose
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2-Deoxy-D-glucose (C6H12O5) — chemical structure, CAS 154-17-6; Life Science, fine chemical supplied by Tech Serve Solutions
Biochemicals and ReagentsCarbohydratesCarbohydrates A to ZCarbohydrates D-FGlycobiologyInhibitorsInhibitors and SubstratesMolecular BiologyMonosaccharideProteomics More...
01 /Applications

Metabolic Research

Utilised as a tool to investigate glucose uptake and metabolism pathways in various cell types and biological systems. Its inhibitory action on glycolysis makes it valuable for studying cellular energetics.

Cancer Research

Employed in studies exploring the Warburg effect and targeting cancer cell metabolism. 2-Deoxy-D-glucose can disrupt energy production in rapidly dividing cancer cells, making it a subject of preclinical investigation.

Glycobiology Studies

Serves as a probe for understanding carbohydrate-protein interactions and the role of specific glycosylation patterns in biological functions and post-translational modifications.

Biochemical Assays

Used as a standard or inhibitor in various biochemical assays designed to measure enzymatic activity related to glucose metabolism or carbohydrate processing.

02 /Properties
Molecular weight164.16
Empirical formulaC6H12O5
Assay≥98% (GC)
SolubilityDo you have solubility information on this product that you would like to share?
Impurities tested≤0.001% Phosphorus (P)<0.1% Insoluble matter
Melting point146-147 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3
Cation tracesAl: ≤0.0005%Ca: ≤0.003%Cu: ≤0.0005%Fe: ≤0.0005%K: ≤0.005%Mg: ≤0.0005%NH4+: ≤0.05%Na: ≤0.005%Pb: ≤0.001%Zn: ≤0.0005%
Anion traceschloride (Cl-): ≤0.05%sulfate (SO42-): ≤0.05%
Ignition residue<0.1%

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
154-17-6
MDL number
MFCD00151328
PubChem substance
24893732
Beilstein registry
1723331
05 /Additional specifications
Product LineBioXtra
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 2-Deoxy-D-glucose used for?

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2-Deoxy-D-glucose (CAS: 154-17-6) is primarily used in biochemical research to investigate glucose metabolism, cellular energetics, and as a tool in cancer and glycobiology studies due to its inhibitory effects on glycolysis.

What are the CAS number and formula for 2-Deoxy-D-glucose?

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The CAS number for 2-Deoxy-D-glucose is 154-17-6, and its molecular formula is C6H12O5.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Deoxy-D-glucose with an assay of ≥98% (GC). This product is not guaranteed to be USP, BP, or EP grade.

How should 2-Deoxy-D-glucose be handled?

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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter due to potential respiratory irritation. It carries a WGK rating of 3 in Germany, indicating high environmental hazard.

Is 2-Deoxy-D-glucose exported by TSS?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Deoxy-D-glucose.

How can I request a quote or sample for 2-Deoxy-D-glucose?

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To request a quote or sample for 2-Deoxy-D-glucose, please contact our sales team through the website or via phone.

Need 2-Deoxy-D-glucose in a specific grade or volume?