2-Ethoxy-2-(2-naphthyl)acetonitrile

CAS 33224-80-5C14H13NOBiochemicals & Reagents

2-Ethoxy-2-(2-naphthyl)acetonitrile (CAS: 33224-80-5) is a chemical compound with the molecular formula C14H13NO and a molecular weight of 211.26 g/mol. It is primarily utilised as a fluorogenic substrate in assays designed to study cytochrome P450 enzyme activity. This compound plays a role in biochemical research and the development of diagnostic tools.

IUPAC: α-Ethoxy-2-naphthaleneacetonitrile

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2-Ethoxy-2-(2-naphthyl)acetonitrile (C14H13NO) — chemical structure, CAS 33224-80-5; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Cytochrome P450 Assays

This compound serves as a fluorogenic substrate for investigating the activity of cytochrome P450 enzymes. These enzymes are critical in drug metabolism and detoxification processes.

Biochemical Research

Utilised in biochemical laboratories for research purposes, particularly in studies involving enzyme kinetics and biological pathway analysis.

Fluorescent Labeling

As a fluorescent probe, it can be employed in various analytical techniques where fluorescence detection is required to monitor specific biological activities or molecular interactions.

02 /Properties

Molecular weight	211.26
Empirical formula	C14H13NO
Assay	≥95.0% (HPLC)
Application	2-Ethoxy-2-(2-naphthyl)acetonitrile is a fluorogenic substrate for use in cytochrome P450 assays.

03 /Safety & handling

GHS hazard pictogram: Environmental hazard (GHS09) — Environmental hazard

Warning

Hazard statements

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment

Protective equipment	Eyeshields, Gloves
Transport (UN / ADR)	UN 3077 9 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	N
Risk statements (R)	50/53
Safety statements (S)	60-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

33224-80-5

MDL number

MFCD08277004

05 /Additional specifications

Fluorescence	λex 227 nm; λem 336 nm in methanol

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 2-Ethoxy-2-(2-naphthyl)acetonitrile used for?

2-Ethoxy-2-(2-naphthyl)acetonitrile is used as a fluorogenic substrate in cytochrome P450 assays and for general biochemical research, functioning as a fluorescent probe.

What are the CAS number and molecular formula?

The CAS number for 2-Ethoxy-2-(2-naphthyl)acetonitrile is 33224-80-5, and its molecular formula is C14H13NO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2-Ethoxy-2-(2-naphthyl)acetonitrile with a purity of ≥95.0% by HPLC. We do not represent this product as USP, BP, or EP grade.

How should 2-Ethoxy-2-(2-naphthyl)acetonitrile be handled safely?

This compound is classified with GHS09 symbol and a Warning signal word, carrying hazard statement H400 (Very toxic to aquatic life). Handle with eyeshields and gloves, and avoid release into the environment (P273). Consult the Safety Data Sheet for comprehensive handling information.

Is this chemical suitable for export?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Ethoxy-2-(2-naphthyl)acetonitrile. It is shipped as UN 3077, Class 9, Packing Group III.