2-Cyanophenylboronic acid MIDA ester
2-Cyanophenylboronic acid MIDA ester (CAS: 1257739-16-4) is an organoboron compound with the molecular formula C12H11BN2O4. This stable MIDA ester serves as a valuable building block in organic synthesis, particularly for cross-coupling reactions. Its robust structure allows for controlled reactivity, making it suitable for the precise construction of complex molecules in pharmaceutical research and materials science.
- IUPAC
- 2-(6-Methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzonitrile
Suzuki-Miyaura Cross-Coupling Reactions
This compound is an effective coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds. It is particularly useful within the context of MIDA boronates, offering advantages in stability and handling compared to more reactive boronic acids.
Organic Synthesis Building Block
As a functionalised aryl boronate ester, it acts as a versatile intermediate for constructing diverse organic frameworks. Its utility spans the synthesis of potential pharmaceutical candidates and novel organic materials.
MIDA Boronate Chemistry
It exemplifies the utility of MIDA (N-methyliminodiacetic acid) protected boronic acids. These derivatives are known for their enhanced stability, ease of purification, and controlled release of the active boronic acid under specific reaction conditions.
| Molecular weight | 258.04 |
|---|---|
| Empirical formula | C12H11BN2O4 |
| Assay | 97% |
| Application | Suzuki Cross-Coupling with MIDA Boronates |
| Melting point | 207-212 °C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Cyanophenylboronic acid MIDA ester used for?
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2-Cyanophenylboronic acid MIDA ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds.
What are the CAS number and formula for 2-Cyanophenylboronic acid MIDA ester?
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The CAS number is 1257739-16-4, and its molecular formula is C12H11BN2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Cyanophenylboronic acid MIDA ester with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should 2-Cyanophenylboronic acid MIDA ester be handled?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
Is 2-Cyanophenylboronic acid MIDA ester a controlled substance?
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The provided data does not indicate that 2-Cyanophenylboronic acid MIDA ester is a controlled substance.
How is 2-Cyanophenylboronic acid MIDA ester packed and exported?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging for the safe transport and international shipment of chemicals like 2-Cyanophenylboronic acid MIDA ester.
How can I request a quote or sample?
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To request a quote or sample of 2-Cyanophenylboronic acid MIDA ester, please use the contact form on the Tech Serve Solutions website or contact our sales department directly.
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