2-(Chloromethyl)quinoline hydrochloride
2-(Chloromethyl)quinoline hydrochloride (CAS 3747-74-8) is a halogenated heterocyclic compound with the molecular formula C10H8ClN · HCl and a molecular weight of 214.09 g/mol. It serves as a valuable building block in organic synthesis, particularly in the preparation of more complex quinoline derivatives. This reagent is essential for researchers and chemists engaged in the development of novel chemical entities within pharmaceutical and material science applications.
- IUPAC
- α-Chloroquinaldine hydrochloride
- Synonyms
- α-Chloroquinaldine hydrochloride

Organic Synthesis Intermediate
Used as a key intermediate in the synthesis of various organic compounds, facilitating the introduction of the quinoline moiety into target molecules.
Heterocyclic Chemistry Research
Employed in academic and industrial research for the construction of diverse heterocyclic frameworks, leveraging its reactive chloromethyl group.
Pharmaceutical Intermediate Development
A useful building block in the multi-step synthesis of potential pharmaceutical agents and drug candidates, particularly those incorporating quinoline structures.
| Molecular weight | 214.09 |
|---|---|
| Empirical formula | C10H8ClN · HCl |
| Assay | 97% |
| Melting point | 183-187 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-38-41-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Chloromethyl)quinoline hydrochloride used for?
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2-(Chloromethyl)quinoline hydrochloride is primarily used as a building block and intermediate in organic synthesis, especially for creating complex quinoline derivatives and in the development of pharmaceutical agents.
What are the CAS number and molecular formula for 2-(Chloromethyl)quinoline hydrochloride?
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The CAS number is 3747-74-8, and the molecular formula is C10H8ClN · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Chloromethyl)quinoline hydrochloride with an assay of 97%. This product is intended for laboratory and research use, and TSS does not represent it as USP, BP, or EP grade.
How should 2-(Chloromethyl)quinoline hydrochloride be handled safely?
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This compound is a Danger hazard, causing serious eye damage (H318), is harmful if swallowed (H302), causes skin irritation (H315), and may cause an allergic skin reaction (H317). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, faceshields, and gloves.
Is 2-(Chloromethyl)quinoline hydrochloride a controlled substance?
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The provided data does not indicate that 2-(Chloromethyl)quinoline hydrochloride is a controlled substance.
How is 2-(Chloromethyl)quinoline hydrochloride packed and shipped?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing and shipping procedures for chemicals like 2-(Chloromethyl)quinoline hydrochloride, adhering to international regulations for safe transport.
How can I request a quote or sample of 2-(Chloromethyl)quinoline hydrochloride?
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You can request a quote or sample by contacting our sales department directly through the Tech Serve Solutions website or by calling our customer service line.
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