3-(4-Hydroxyphenyl)propionic acid
3-(4-Hydroxyphenyl)propionic acid (CAS 501-97-3) is a carboxylic acid with the molecular formula HOC6H4CH2CH2CO2H and a molecular weight of 166.17 g/mol. This compound, also known as Phloretic acid, is characterised by its phenolic hydroxyl group and propionic acid moiety. It is utilized as a building block in chemical synthesis and finds application in biochemical research, particularly in fluorescence-based assays.
- IUPAC
- Phloretic acid
- Synonyms
- Phloretic acid

Chemical Synthesis Intermediate
This compound serves as a valuable building block in organic synthesis. Its functional groups allow for further chemical modifications to create more complex molecules for various research and development purposes.
Biochemical Research
It is employed in biochemical studies, particularly as a substrate in fluorescence-based enzyme assays. Its fluorescence properties can be utilized for detection and quantification in biological systems.
Fluorescence Assays
The compound exhibits specific fluorescence characteristics (λex 320 nm; λem 404 nm) when used in conjunction with enzymes like peroxidase and hydrogen peroxide, making it suitable for spectroscopic applications.
| Molecular weight | 166.17 |
|---|---|
| Linear formula | HOC6H4CH2CH2CO2H |
| Assay | ≥98.0% (T) |
| Melting point | 127-129 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 320 nm; λem 404 nm in 0.1 M Tris pH 8.5, 2 mM H2O2, peroxidase |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(4-Hydroxyphenyl)propionic acid used for?
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3-(4-Hydroxyphenyl)propionic acid is used as a building block in chemical synthesis and in biochemical research, particularly for fluorescence-based enzyme assays.
What is the CAS number and chemical formula for 3-(4-Hydroxyphenyl)propionic acid?
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The CAS number is 501-97-3 and the chemical formula is HOC6H4CH2CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(4-Hydroxyphenyl)propionic acid with an assay of ≥98.0% (T). TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling this chemical?
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This compound is a warning hazardous substance. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves, should be worn.
How is 3-(4-Hydroxyphenyl)propionic acid packed, shipped, and exported?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging and shipping details are confirmed upon order placement, adhering to international regulations.
How can I request a sample or quote for 3-(4-Hydroxyphenyl)propionic acid?
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To request a sample or a quotation, please contact our sales department through the website or via direct email, providing your specific requirements.
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