2-Bromoquinoline
2-Bromoquinoline (CAS: 2005-43-8), with the molecular formula C9H6BrN and a molecular weight of 208.05 g/mol, is a halogenated heterocyclic building block. It serves as a valuable intermediate in organic synthesis. This compound is primarily utilised in research and development for the creation of novel chemical entities and advanced materials, particularly within the pharmaceutical and fine chemical sectors. Its reactivity is leveraged in various cross-coupling reactions and heterocycle functionalisation.
Organic Synthesis Intermediate
2-Bromoquinoline is a key reagent in the synthesis of more complex organic molecules. Its bromo-substituent allows for facile introduction into various carbon-carbon bond-forming reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
Pharmaceutical Research
This compound finds application in the development of novel pharmaceutical agents. The quinoline core is a common structural motif in many biologically active compounds, and 2-bromoquinoline facilitates its incorporation into drug candidates.
Materials Science
The unique electronic properties of the quinoline system make 2-bromoquinoline a useful building block for the synthesis of functional materials, including organic semiconductors and luminescent compounds.
| Molecular weight | 208.05 |
|---|---|
| Empirical formula | C9H6BrN |
| Assay | 95% |
| Melting point | 44-48 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 22-26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromoquinoline used for?
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2-Bromoquinoline is primarily used as an intermediate in organic synthesis, particularly for the construction of complex molecules in pharmaceutical research and materials science. It is valuable for introducing the quinoline moiety into larger structures via cross-coupling reactions.
What is the CAS number and formula for 2-Bromoquinoline?
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The CAS number for 2-Bromoquinoline is 2005-43-8, and its molecular formula is C9H6BrN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromoquinoline with a minimum assay of 95%. This product is suitable for research and synthesis purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should 2-Bromoquinoline be handled safely?
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2-Bromoquinoline is classified as Dangerous (Danger). It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid breathing dust.
How is 2-Bromoquinoline packed and shipped?
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2-Bromoquinoline is carefully packed according to international shipping regulations for chemical substances. TSS is experienced in exporting fine chemicals globally.
How can I request a quote or sample of 2-Bromoquinoline?
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To request a quote or a sample of 2-Bromoquinoline, please contact the TSS sales team via the website or by phone, providing your required quantity and delivery details.
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