2-Bromopyrimidine
2-Bromopyrimidine (CAS: 4595-60-2, C4H3BrN2) is a halogenated heterocyclic compound with a molecular weight of 158.98 g/mol. It serves as a valuable building block in organic synthesis, particularly for the creation of more complex pyrimidine derivatives. Its utility is demonstrated in cross-coupling reactions, enabling the construction of advanced molecular architectures for research and development in various chemical fields.
Organic Synthesis Intermediate
2-Bromopyrimidine is employed as a key intermediate in the synthesis of diverse organic molecules. Its reactive bromine atom facilitates cross-coupling reactions, allowing for the introduction of pyrimidine moieties into larger structures.
Synthesis of Fluorene Derivatives
This compound has been utilised in the preparation of complex organic structures, such as 2,7-bis(2-pyrimidyl)-9,9-dihexylfluorene, through palladium-catalysed cross-coupling reactions with organoboron compounds.
Heterocyclic Chemistry Research
As a halogenated heterocycle, 2-Bromopyrimidine is a useful reagent for researchers exploring novel synthetic routes and functionalising heterocyclic systems for advanced materials or pharmaceutical lead discovery.
| Molecular weight | 158.98 |
|---|---|
| Empirical formula | C4H3BrN2 |
| Assay | 95% |
| Storage temperature | −20°C |
| Application | 2-Bromopyrimidine was used in the synthesis of 2,7-bis(2-pyrimidyl)-9,9-dihexylfluorene by cross-coupling with 9,9-dihexylfluorene-2,7-diboronic acid1. |
| Melting point | 55-57 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromopyrimidine used for?
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2-Bromopyrimidine is primarily used as a building block in organic synthesis, notably in cross-coupling reactions for the preparation of complex heterocyclic compounds.
What is the CAS number and chemical formula for 2-Bromopyrimidine?
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The CAS number is 4595-60-2 and the chemical formula is C4H3BrN2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromopyrimidine with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Bromopyrimidine be handled safely?
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2-Bromopyrimidine is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation.
Is 2-Bromopyrimidine a controlled substance?
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The provided data does not indicate that 2-Bromopyrimidine is a controlled substance.
How is 2-Bromopyrimidine packed and exported?
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2-Bromopyrimidine is stored at -20°C. Tech Serve Solutions, as a global supplier, exports chemicals worldwide, adhering to all relevant shipping regulations.
How can I request a sample or quote for 2-Bromopyrimidine?
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To request a sample or a quotation for 2-Bromopyrimidine, please contact our sales department through the website or by phone.
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