5-Methoxytryptamine
5-Methoxytryptamine (CAS: 608-07-1), with the molecular formula C11H14N2O and a molecular weight of 190.24 g/mol, is a key indole derivative. This compound functions as a biochemical tool, particularly noted for its use as an agonist in the study of serotonin receptors, specifically the 5-hydroxytryptamine 1 receptor. Its chemical structure and properties make it valuable in pharmacological research and chemical synthesis.
- IUPAC
- 2-(5-Methoxyindol-3-yl)ethylamine,3-(2-Aminoethyl)-5-methoxyindole,5-Methoxyindole-3-ethanamine,5-MOT,Deacetylmelatonin,NSC 56422
- Synonyms
- 2-(5-Methoxyindol-3-yl)ethylamine3-(2-Aminoethyl)-5-methoxyindole5-Methoxyindole-3-ethanamine5-MOTDeacetylmelatoninNSC 56422

Pharmacological Research
Utilised as an agonist to investigate the pharmacological profile of the 5-hydroxytryptamine 1 receptor. This aids in understanding receptor function and developing novel therapeutics targeting serotonergic pathways.
Chemical Synthesis
Serves as a building block in the synthesis of more complex organic molecules. Its indole core and methoxy substitution offer specific reactivity for creating diverse chemical structures.
Cell Biology Studies
Employed in research related to cell biology due to its role as a signalling molecule or its structural similarity to endogenous compounds.
| Molecular weight | 190.24 |
|---|---|
| Empirical formula | C11H14N2O |
| Assay | 97% |
| Application | 5-Methoxytryptamine was used as an agonist in the study of pharmacological profile of the 5-hydroxytryptamine 1 receptor1. |
| Melting point | 121-123 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HTR1A(3350), HTR2A(3356), HTR2C(3358)rat ... Htr2a(29595), Htr2c(25187), Htr7(65032) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methoxytryptamine used for?
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5-Methoxytryptamine (CAS: 608-07-1) is primarily used as an agonist in pharmacological studies, particularly for investigating the 5-hydroxytryptamine 1 receptor. It also serves as a building block in chemical synthesis and is used in cell biology research.
What is the CAS number and molecular formula for 5-Methoxytryptamine?
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The CAS number for 5-Methoxytryptamine is 608-07-1, and its molecular formula is C11H14N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methoxytryptamine with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety concerns when handling 5-Methoxytryptamine?
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5-Methoxytryptamine is classified with a GHS07 symbol and a 'Warning' signal word. It carries the hazard statement H302, indicating it is harmful if swallowed. Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used during handling.
Is 5-Methoxytryptamine a controlled substance?
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Based on the provided data, there is no indication that 5-Methoxytryptamine (CAS: 608-07-1) is a controlled substance. However, customers are advised to verify its regulatory status in their specific jurisdiction.
How is 5-Methoxytryptamine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. 5-Methoxytryptamine is packed and shipped according to international regulations for chemical transport. Please contact us for specific export details.
How can I request a quote or sample for 5-Methoxytryptamine?
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To request a quote or sample of 5-Methoxytryptamine, please use the 'Request a Quote' or 'Request a Sample' functionality on our website, or contact our sales department directly.
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