2-Bromophenylboronic acid
2-Bromophenylboronic acid (CAS: 244205-40-1, Formula: BrC6H4B(OH)2) is an organoboronic acid with a molecular weight of 200.83. It serves as a valuable reagent in organic synthesis, notably catalysing the formation of amide bonds between amines and carboxylic acids. Its utility extends to various chemical synthesis applications, positioning it as a key intermediate for advanced chemical research and development.
- IUPAC
- o-Bromophenylboronic acid
- Synonyms
- o-Bromophenylboronic acid
Amide Bond Formation
This boronic acid derivative is employed as a catalyst in the synthesis of amide bonds. It facilitates the coupling reaction between amines and carboxylic acids, a fundamental transformation in organic chemistry.
Organic Synthesis Intermediate
As an aryl boronic acid, 2-Bromophenylboronic acid is a versatile building block. It participates in cross-coupling reactions, enabling the construction of complex organic molecules for various research and industrial purposes.
Catalysis in Chemical Reactions
The compound functions as a catalyst, promoting specific chemical transformations. Its catalytic activity is particularly relevant in reactions requiring the formation of new carbon-heteroatom bonds.
| Molecular weight | 200.83 |
|---|---|
| Linear formula | BrC6H4B(OH)2 |
| Assay | ≥95.0% |
| Application | Catalyzes the formation of amide bonds from amines and carboxylic acids. |
| Melting point | 113 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Greener Alternative Product Characteristics | Catalysis |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromophenylboronic acid used for?
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2-Bromophenylboronic acid is primarily used as a catalyst for the formation of amide bonds from amines and carboxylic acids, and as a versatile intermediate in organic synthesis and chemical research.
What is the CAS number and formula for 2-Bromophenylboronic acid?
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The CAS number for 2-Bromophenylboronic acid is 244205-40-1, and its linear formula is BrC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromophenylboronic acid with an assay of ≥95.0%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
What are the safety considerations when handling 2-Bromophenylboronic acid?
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2-Bromophenylboronic acid is classified with the GHS symbol GHS07 and the signal word Warning. It carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, ensuring adequate ventilation and avoiding contact with skin, eyes, and inhalation.
How is 2-Bromophenylboronic acid shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Bromophenylboronic acid, ensuring compliant and secure international shipment.
How can I request a sample or quote for 2-Bromophenylboronic acid?
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To request a sample or a quote for 2-Bromophenylboronic acid, please contact our sales team through the website or via direct inquiry.
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