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2-Bromophenylboronic acid MIDA ester

CAS 1257649-57-2C11H11BBrNO4Chemical Synthesis

2-Bromophenylboronic acid MIDA ester (CAS: 1257649-57-2) is a valuable organoboron compound with the empirical formula C11H11BBrNO4 and a molecular weight of 311.92 g/mol. This Aryl MIDA Boronate derivative serves as a key intermediate in organic synthesis, particularly in cross-coupling reactions. Its utility lies in enabling efficient carbon-carbon bond formation, making it a useful reagent in the development of complex organic molecules within research and development settings.

IUPAC
2-(2-Bromophenyl)-6-methyl-1,3,6,2-dioxazaboracane-4,8-dione
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2-Bromophenylboronic acid MIDA ester (C11H11BBrNO4) — chemical structure, CAS 1257649-57-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Aryl MIDA BoronatesChemical SynthesisMIDA BoronatesOrganometallic Reagents
01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

2-Bromophenylboronic acid MIDA ester is primarily employed as a coupling partner in Suzuki-Miyaura cross-coupling reactions. This allows for the efficient synthesis of biaryl compounds and other substituted aromatic systems.

Organic Synthesis Intermediate

As an Aryl MIDA Boronate, it functions as a stable and versatile building block in multi-step organic syntheses. The MIDA ester functionality offers improved handling and stability compared to free boronic acids.

Pharmaceutical Research

This compound can be utilised in the research and development of novel pharmaceutical agents, where precise construction of molecular architectures is crucial for biological activity.

02 /Properties
Molecular weight311.92
Empirical formulaC11H11BBrNO4
Assay95%
ApplicationSuzuki Cross-Coupling with MIDA Boronates
Melting point205-213 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
1257649-57-2
MDL number
MFCD11215210
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Bromophenylboronic acid MIDA ester used for?

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2-Bromophenylboronic acid MIDA ester is used as a key intermediate in Suzuki-Miyaura cross-coupling reactions and general organic synthesis for the construction of complex organic molecules.

What is the CAS number and formula for 2-Bromophenylboronic acid MIDA ester?

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The CAS number is 1257649-57-2 and the empirical formula is C11H11BBrNO4.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Bromophenylboronic acid MIDA ester with an assay of 95%. We do not represent this product as USP, BP, or EP grade.

How should 2-Bromophenylboronic acid MIDA ester be handled safely?

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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid ingestion as it may be harmful (H302).

Is this chemical suitable for export?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Bromophenylboronic acid MIDA ester.

How can I request a sample or quote?

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Please contact our sales department via our website or by phone to request a sample or a formal quotation for 2-Bromophenylboronic acid MIDA ester.

Need 2-Bromophenylboronic acid MIDA ester in a specific grade or volume?