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2-Bromoacetamide

CAS 683-57-8BrCH2CONH2Chemical Synthesis

2-Bromoacetamide (CAS: 683-57-8) is an organic compound with the linear formula BrCH2CONH2 and a molecular weight of 137.96 g/mol. It functions as a valuable building block and reagent in organic synthesis. This compound is primarily employed in the preparation of more complex molecules, serving as a precursor in various chemical transformations. Its utility is documented in scientific literature for applications such as the synthesis of specific carbamic acid esters and as an inactivator for dehydropeptidase I.

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2-Bromoacetamide (BrCH2CONH2) — chemical structure, CAS 683-57-8; Chemistry, fine chemical supplied by Tech Serve Solutions
AmidesBuilding BlocksC2 to C7Carbonyl CompoundsChemical Synthesis
01 /Applications

Synthesis of Carbamic Acid Esters

2-Bromoacetamide has been utilised as a key reactant in the preparation of (2-carbamoylmethoxy-5-chloro-benzyl)-carbamic acid tert-butyl ester, demonstrating its role in constructing complex organic structures.

Precursor for Enzyme Inactivators

The compound serves as a precursor for the synthesis of dehydropeptidase I inactivators. This application highlights its significance in biochemical research and potentially in drug discovery.

Organic Synthesis Building Block

As a bifunctional molecule containing both a reactive bromine atom and an amide group, 2-Bromoacetamide is a versatile building block for introducing the acetamide moiety into various organic frameworks.

02 /Properties
Molecular weight137.96
Linear formulaBrCH2CONH2
Assay≥98.0% (GC)
Application2-Bromoacetamide was used in preparation of (2-carbamoylmethoxy-5-chloro-benzyl)-carbamic acid tert-butyl ester.1 It was aslo used as precursor to dehydropeptidase I inactivator.2
Melting point87-91 °C(lit.)87-91 °C
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P301IF SWALLOWED
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)UN 2923 8/PG 2
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)25-34
Safety statements (S)26-27-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
683-57-8
MDL number
MFCD00008025
PubChem substance
24858176
Beilstein registry
1739073
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Bromoacetamide used for?

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2-Bromoacetamide is used as a building block in organic synthesis, notably in the preparation of specific carbamic acid esters and as a precursor to dehydropeptidase I inactivators.

What is the CAS number and chemical formula for 2-Bromoacetamide?

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The CAS number for 2-Bromoacetamide is 683-57-8 and its linear formula is BrCH2CONH2.

What grade and purity does Tech Serve Solutions supply for 2-Bromoacetamide?

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Tech Serve Solutions supplies 2-Bromoacetamide with a purity of ≥98.0% (GC). This is a research-grade chemical and is not supplied as USP, BP, or EP grade.

How should 2-Bromoacetamide be handled safely?

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2-Bromoacetamide is a hazardous substance. It is classified as Danger, causing severe skin burns and eye damage (H314) and is toxic if swallowed (H301). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, is essential. Handle only in well-ventilated areas and seek immediate medical attention if exposure occurs.

Does Tech Serve Solutions export 2-Bromoacetamide?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Bromoacetamide, and can fulfil export orders worldwide.

How can I request a quote or sample of 2-Bromoacetamide?

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To request a quote or a sample of 2-Bromoacetamide, please contact our sales team through the website or by phone, providing your contact details and the quantity required.

Need 2-Bromoacetamide in a specific grade or volume?