2-Bromo-6-(trifluoromethyl)pyridine
2-Bromo-6-(trifluoromethyl)pyridine (CAS: 189278-27-1, Formula: C6H3BrF3N) is a versatile halogenated heterocyclic building block. With a molecular weight of 225.99 g/mol and an assay of 97%, it serves as a key intermediate in organic synthesis. Its structure, featuring both a bromine atom and a trifluoromethyl group on a pyridine ring, allows for diverse chemical transformations. This compound is primarily utilised in research and development for the synthesis of complex organic molecules, particularly within the pharmaceutical and agrochemical sectors.

Pharmaceutical Intermediate
This compound is employed in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery research. The trifluoromethylpyridine scaffold is present in various biologically active molecules.
Agrochemical Synthesis
It serves as a building block for developing new pesticides, herbicides, and fungicides. The incorporation of fluorine can enhance the efficacy and stability of agrochemical products.
Organic Synthesis Reagent
Utilised as a versatile reagent in complex organic synthesis, enabling the introduction of the 2-bromo-6-(trifluoromethyl)pyridyl moiety into target molecules via various coupling reactions.
Materials Science Research
May be used in the development of novel materials where fluorinated heterocyclic units are desired for specific electronic or optical properties.
| Molecular weight | 225.99 |
|---|---|
| Empirical formula | C6H3BrF3N |
| Assay | 97% |
| Melting point | 48-52 °C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-6-(trifluoromethyl)pyridine used for?
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2-Bromo-6-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It acts as an intermediate for introducing the 2-bromo-6-(trifluoromethyl)pyridyl functional group into more complex molecules.
What are the CAS number and formula for 2-Bromo-6-(trifluoromethyl)pyridine?
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The CAS number for 2-Bromo-6-(trifluoromethyl)pyridine is 189278-27-1, and its chemical formula is C6H3BrF3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-6-(trifluoromethyl)pyridine with a minimum purity of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product documentation.
How should 2-Bromo-6-(trifluoromethyl)pyridine be handled safely?
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2-Bromo-6-(trifluoromethyl)pyridine is classified as Dangerous (GHS06, Signal Word: Danger) with hazard statements H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, must be used. Handle in a well-ventilated area or fume hood.
Is 2-Bromo-6-(trifluoromethyl)pyridine a controlled substance?
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Based on the provided data, there is no indication that 2-Bromo-6-(trifluoromethyl)pyridine is a controlled substance. However, customers should verify local regulations.
How is 2-Bromo-6-(trifluoromethyl)pyridine packed and shipped?
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As a global supplier, Tech Serve Solutions ensures products are packed and shipped in compliance with all relevant international transportation regulations, including UN 2811 classification for toxic solids.
How can I request a sample or quote for 2-Bromo-6-(trifluoromethyl)pyridine?
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To request a sample or a quote for 2-Bromo-6-(trifluoromethyl)pyridine, please contact our sales team through the website or provide your inquiry details via the online contact form.
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