2-Bromo-5′-fluoro-2′-hydroxyacetophenone
2-Bromo-5′-fluoro-2′-hydroxyacetophenone (CAS 126581-65-5) is an organic compound with the molecular formula C8H6BrFO2 and a molecular weight of 233.03 g/mol. This brominated and fluorinated acetophenone derivative serves as a valuable building block in organic synthesis, particularly for the construction of complex molecules in pharmaceutical and agrochemical research. Its reactive functional groups allow for diverse chemical transformations.
- IUPAC
- 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone,5-Fluoro-2-hydroxyphenacyl bromide
- Synonyms
- 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone5-Fluoro-2-hydroxyphenacyl bromide

Pharmaceutical Intermediate
Utilised in the synthesis of novel pharmaceutical compounds. Its structure allows for the introduction of specific functionalities crucial for drug discovery and development.
Agrochemical Research
Serves as a key intermediate in the development of new agrochemicals. Enables the creation of compounds with potential pesticidal or herbicidal activity.
Organic Synthesis Building Block
A versatile reagent in academic and industrial research laboratories for constructing complex organic molecules. Facilitates reactions due to its electrophilic carbonyl and activated aromatic ring.
Material Science
May be employed in the synthesis of specialty materials where fluorinated aromatic structures are beneficial for unique electronic or physical properties.
| Molecular weight | 233.03 |
|---|---|
| Empirical formula | C8H6BrFO2 |
| Assay | 97% |
| Melting point | 87-91 °C |

Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-5′-fluoro-2′-hydroxyacetophenone used for?
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2-Bromo-5′-fluoro-2′-hydroxyacetophenone (CAS 126581-65-5) is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical intermediates and agrochemicals, as well as in material science research.
What is the CAS number and molecular formula for 2-Bromo-5′-fluoro-2′-hydroxyacetophenone?
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The CAS number is 126581-65-5, and the molecular formula is C8H6BrFO2.
What grade and purity does Tech Serve Solutions supply for 2-Bromo-5′-fluoro-2′-hydroxyacetophenone?
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Tech Serve Solutions supplies 2-Bromo-5′-fluoro-2′-hydroxyacetophenone with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Bromo-5′-fluoro-2′-hydroxyacetophenone be handled safely?
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Based on the GHS classification, this compound is harmful if swallowed (H302) and causes serious eye irritation (H319). When handling, wear appropriate personal protective equipment including a dust mask (type N95 or equivalent), eyeshields, faceshields, and gloves. Ensure adequate ventilation.
How is 2-Bromo-5′-fluoro-2′-hydroxyacetophenone packed and exported?
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2-Bromo-5′-fluoro-2′-hydroxyacetophenone is packed securely for transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations for hazardous materials (UN 3335).
How can I request a quote or sample for 2-Bromo-5′-fluoro-2′-hydroxyacetophenone?
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To request a quote or a sample of 2-Bromo-5′-fluoro-2′-hydroxyacetophenone, please contact the Tech Serve Solutions sales team via our website or direct contact details, providing your requirements and shipping information.
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