2-Bromo-5′-chloro-2′-hydroxyacetophenone
2-Bromo-5′-chloro-2′-hydroxyacetophenone (CAS: 52727-99-8) is an organic compound with the molecular formula C8H6BrClO2 and a molecular weight of 249.49 g/mol. This halogenated acetophenone derivative serves as a versatile building block in organic synthesis. It is primarily utilised in research and development laboratories for the preparation of more complex molecules, including potential pharmaceutical intermediates and fine chemicals. Its specific structure lends itself to various chemical transformations.
- IUPAC
- 2-Bromo-1-(5-chloro-2-hydroxyphenyl)ethanone,5-Chloro-2-hydroxyphenacyl bromide
- Synonyms
- 2-Bromo-1-(5-chloro-2-hydroxyphenyl)ethanone5-Chloro-2-hydroxyphenacyl bromide

Organic Synthesis Intermediate
This compound is a valuable intermediate in the synthesis of diverse organic molecules. Its functional groups allow for a range of chemical reactions, making it useful in the development of novel chemical entities.
Pharmaceutical Research
As a building block, 2-Bromo-5′-chloro-2′-hydroxyacetophenone can be employed in the discovery and development of new pharmaceutical agents. It is used in multi-step syntheses to create complex drug candidates.
Fine Chemical Production
The compound finds application in the production of fine chemicals where specific structural motifs are required. It facilitates the creation of specialised chemical compounds for various industrial uses.
| Molecular weight | 249.49 |
|---|---|
| Empirical formula | C8H6BrClO2 |
| Assay | 97% |
| Melting point | 63-67 °C |

Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-5′-chloro-2′-hydroxyacetophenone used for?
+
2-Bromo-5′-chloro-2′-hydroxyacetophenone is primarily used as a building block and intermediate in organic synthesis and pharmaceutical research for the creation of more complex molecules.
What is the CAS number and molecular formula for 2-Bromo-5′-chloro-2′-hydroxyacetophenone?
+
The CAS number is 52727-99-8 and the molecular formula is C8H6BrClO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Bromo-5′-chloro-2′-hydroxyacetophenone with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Bromo-5′-chloro-2′-hydroxyacetophenone be handled?
+
This compound is classified as Danger with hazards H301 (Toxic if swallowed) and H319 (Causes serious eye irritation). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, face shields, and gloves. Ensure good ventilation.
Is this chemical suitable for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Bromo-5′-chloro-2′-hydroxyacetophenone, adhering to all necessary shipping regulations including UN 2811 classification.
How can I request a sample or quote for 2-Bromo-5′-chloro-2′-hydroxyacetophenone?
+
To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis