2-Bromo-3′-methoxyacetophenone
2-Bromo-3′-methoxyacetophenone (CAS: 5000-65-7) is an organic compound with the molecular formula C9H9BrO2 and a molecular weight of 229.07 g/mol. This brominated ketone functions as a valuable alkylating agent and building block in organic synthesis. It is particularly noted for its utility in stabilising active metabolites in biological samples, facilitating accurate analysis and research. Available from Tech Serve Solutions with an assay of 98%, it is typically stored under refrigerated conditions.
- IUPAC
- 3′-Methoxyphenacyl bromide
- Synonyms
- 3′-Methoxyphenacyl bromide
Stabilisation of Active Metabolites
2-Bromo-3′-methoxyacetophenone is employed as an alkylating agent to stabilise active metabolites, such as clopidogrel AM, in human plasma. This ensures the integrity of the metabolite during sample processing and storage for analytical purposes.
Derivatisation for Analysis
The compound is utilised in the derivatisation of active metabolites found in blood. This process enhances their stability, which is crucial for accurate quantification and study during research and diagnostic procedures.
Organic Synthesis Building Block
As a functionalised ketone, 2-Bromo-3′-methoxyacetophenone serves as a versatile building block in the synthesis of more complex organic molecules. Its reactive bromide and carbonyl groups allow for various chemical transformations.
| Molecular weight | 229.07 |
|---|---|
| Linear formula | CH3OC6H4COCH2Br |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Application | 2-bromo-3′-methoxyacetophenone, an alkylating agent, has been used to stabilize clopidogrel active metabolite (AM) in human plasma1. It has also been used in the derivatisation of active metabolites in blood to ensure its stability during sample processing and storage2. |
| Melting point | 60-62 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-3′-methoxyacetophenone used for?
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2-Bromo-3′-methoxyacetophenone is primarily used as an alkylating agent to stabilise active metabolites in biological samples like plasma and blood, aiding in their analysis. It also functions as a building block in organic synthesis.
What is the CAS number and molecular formula for 2-Bromo-3′-methoxyacetophenone?
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The CAS number is 5000-65-7, and its linear formula is C9H9BrO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-3′-methoxyacetophenone with an assay of 98%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
What are the main safety hazards associated with 2-Bromo-3′-methoxyacetophenone?
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This compound is classified as Danger, with hazard statements H314 (Causes severe skin burns and eye damage) and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, must be used.
How is 2-Bromo-3′-methoxyacetophenone typically stored and shipped?
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2-Bromo-3′-methoxyacetophenone should be stored at 2-8°C. It is shipped in compliance with relevant dangerous goods regulations (UN 3261).
How can I request a quote or sample for 2-Bromo-3′-methoxyacetophenone?
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Please contact our sales department via the website or phone to request a quote or sample of 2-Bromo-3′-methoxyacetophenone.
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