2-Aminothiophenol
2-Aminothiophenol (CAS: 137-07-5), with the linear formula H₂NC₆H₄SH and a molar mass of 125.19 g/mol, is a key organic building block. This sulfur compound, also known as 2-aminobenzenethiol, serves as a valuable intermediate in chemical synthesis. It finds application in the preparation of complex organic molecules, including heterocyclic compounds and functionalised nanoparticles for sensing applications.
- IUPAC
- 2-Aminobenzenethiol,2-Aminophenyl mercaptan,2-Mercaptoaniline
Synthesis of Stable Phosphonium Ylides
2-Aminothiophenol has been employed in one-pot synthetic strategies to efficiently generate stable phosphonium ylides, valuable intermediates in organic chemistry.
Preparation of Benzothiazole Derivatives
This compound acts as a precursor in the synthesis of various benzothiazole derivatives, such as 2-[(2-benzothiazolylmethyl)thio]-benzenamine, through established reaction pathways.
Functionalisation of Nanoparticles for Sensing
2-Aminothiophenol can be used to functionalise silver nanoparticles, enabling their application in surface-enhanced Raman scattering (SERS) for biological pH sensing.
| Molecular weight | 125.19 |
|---|---|
| Linear formula | H2NC6H4SH |
| Assay | ≥95.0% (GC) |
| Boiling point | 70-72 °C/0.2 mmHg(lit.) |
| Density | 1.17 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.642(lit.)n20/D 1.642 |
| Application | 2-Aminothiophenol was used in one-pot synthesis of stable phosphonium ylides1. It was also used in the synthesis of 2-[(2-benzothiazolylmethyl)thio]-benzenamine2. It was used to functionalize silver nano particles for biological pH sensing based on surface enhanced Raman scattering3. |
| Melting point | 16-20 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P501Dispose of contents and container per local regulations
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | UN 1760 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C,N |
| Risk statements (R) | 22-34-50/53 |
| Safety statements (S) | 26-36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Aminothiophenol used for?
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2-Aminothiophenol is used in organic synthesis, including the preparation of stable phosphonium ylides, benzothiazole derivatives, and for functionalising nanoparticles for sensing applications.
What are the CAS number and chemical formula for 2-Aminothiophenol?
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The CAS number for 2-Aminothiophenol is 137-07-5, and its linear formula is H₂NC₆H₄SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Aminothiophenol with an assay of ≥95.0% (GC). This is a technical grade material and is not represented as USP, BP, or EP.
How should 2-Aminothiophenol be handled safely?
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2-Aminothiophenol is a corrosive substance (H314) that is harmful if swallowed (H302) and toxic to aquatic life with long-lasting effects (H410). Handle with appropriate personal protective equipment, including gloves, goggles, and a suitable respirator, in a well-ventilated area. Avoid release to the environment.
How is 2-Aminothiophenol packed, shipped, and exported?
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2-Aminothiophenol is typically packed in robust containers suitable for hazardous materials and is shipped and exported in compliance with international transportation regulations for dangerous goods (UN 1760, Class 8, PG III).
How can I request a quote or sample of 2-Aminothiophenol?
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To request a quote or sample of 2-Aminothiophenol, please contact our sales team through the website or by phone, providing your details and requirements.
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