2,5-Dimethylphenylboronic acid
2,5-Dimethylphenylboronic acid (CAS: 85199-06-0) is an organoboron compound with the molecular formula (CH₃)₂C₆H₃B(OH)₂ and a molecular weight of 149.98 g/mol. This disubstituted aryl boronic acid serves as a valuable reactant in organic synthesis. It is notably employed in Friedel-Crafts alkylation reactions and as a coupling partner in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds.
- IUPAC
- p-Xyleneboronic acid
- Synonyms
- (CH3)2C6H3B(OH)2
Suzuki-Miyaura Coupling
2,5-Dimethylphenylboronic acid is a key reactant in palladium-catalysed Suzuki-Miyaura cross-coupling reactions. This application allows for the efficient formation of carbon-carbon bonds between aryl or vinyl halides and organoboron compounds.
Friedel-Crafts Alkylation
The compound can be utilised as a reactant in Friedel-Crafts alkylation reactions. This electrophilic aromatic substitution permits the introduction of alkyl groups onto aromatic rings.
Organic Synthesis Intermediate
As a functionalised boronic acid, it serves as a versatile building block in multi-step organic syntheses, enabling the construction of complex molecules for research and development.
| Molecular weight | 149.98 |
|---|---|
| Linear formula | (CH3)2C6H3B(OH)2 |
| Application | Reactant for:• Friedel-Crafts alkylation1• Suzuki-Miyaura coupling2 |
| Melting point | 186-191 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dimethylphenylboronic acid used for?
+
2,5-Dimethylphenylboronic acid is primarily used as a reactant in organic synthesis, particularly in Friedel-Crafts alkylation and Suzuki-Miyaura coupling reactions to form carbon-carbon bonds.
What is the CAS number and formula for 2,5-Dimethylphenylboronic acid?
+
The CAS number for 2,5-Dimethylphenylboronic acid is 85199-06-0, and its linear formula is (CH₃)₂C₆H₃B(OH)₂.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,5-Dimethylphenylboronic acid with a typical purity of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,5-Dimethylphenylboronic acid be handled?
+
Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Please consult the Safety Data Sheet (SDS) for comprehensive handling and safety information.
Is 2,5-Dimethylphenylboronic acid a hazardous substance?
+
According to the GHS classification, this compound is classified under Water Hazard Class 3 (WGK 3) in Germany, indicating it is hazardous to water. Users should take precautions to prevent its release into the environment.
How is 2,5-Dimethylphenylboronic acid packed and shipped?
+
Tech Serve Solutions packs and ships chemicals according to international transport regulations, ensuring safe transit. We export globally to support research and industrial needs.
How can I request a sample or quote for 2,5-Dimethylphenylboronic acid?
+
To request a sample or a formal quotation, please contact our sales department through the website or by calling us directly. Please reference the product name and CAS number (85199-06-0).
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis