2,5-Dihydroxycinnamic acid methyl ester
2,5-Dihydroxycinnamic acid methyl ester (CAS 63177-57-1) is a yellow crystalline compound with a molecular weight of 194.18 g/mol. This methyl ester of 2,5-dihydroxycinnamic acid is recognised as an analog of Erbstatin and is primarily employed in biochemical research. Its applications span cell biology and signalling studies, particularly concerning Epidermal Growth Factor Receptor (EGFR) pathways. TSS supplies this compound with a purity of ≥95%.
- IUPAC
- Erbstatin analog,Methyl 2,5-dihydroxycinnamate
- Synonyms
- Erbstatin analogMethyl 2,5-dihydroxycinnamate
EGFR Pathway Research
2,5-Dihydroxycinnamic acid methyl ester acts as an analog of Erbstatin, a known inhibitor of Epidermal Growth Factor Receptor (EGFR). This makes it a valuable tool for researchers studying cell signalling and cancer biology, particularly the role of EGFR in cell proliferation and survival.
Biochemical Assays
As a bioactive small molecule, this compound can be used in various biochemical assays. Its solubility in methanol and alkaline solutions facilitates its use in in vitro experimental setups for studying enzyme inhibition and protein kinase activity.
Cell Biology Studies
This chemical serves as a reagent in cell biology research, aiding investigations into cellular processes, growth factor signalling, and related therapeutic targets. Its specific activity provides insights into kinase pathways.
| Molecular weight | 194.18 |
|---|---|
| Empirical formula | C10H10O4 |
| Assay | ≥95% |
| Form | crystalline |
| Colour | yellow |
| Solubility | 0.1 M NaOH: solubleH2O: insolublemethanol: soluble |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38 |
| Safety statements (S) | 22-26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dihydroxycinnamic acid methyl ester used for?
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2,5-Dihydroxycinnamic acid methyl ester (CAS 63177-57-1) is used in biochemical research, particularly for studying Epidermal Growth Factor Receptor (EGFR) pathways, as an analog of Erbstatin, and in cell signalling and kinase inhibitor studies.
What are the CAS number and formula for 2,5-Dihydroxycinnamic acid methyl ester?
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The CAS number for 2,5-Dihydroxycinnamic acid methyl ester is 63177-57-1. Its empirical formula (Hill Notation) is C10H10O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Dihydroxycinnamic acid methyl ester with a minimum purity of 95% (assay ≥95%). This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 2,5-Dihydroxycinnamic acid methyl ester be handled safely?
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Handling requires caution due to significant hazards. Use appropriate personal protective equipment including eyeshields, face shields, gloves, and P2 respirator cartridges. Avoid inhalation, skin contact, and eye contact. Specific measures include P261 (Avoid breathing dust), P280 (Wear protective gloves/protective clothing), P301 + P310 (IF SWALLOWED: Immediately call a POISON CENTER/doctor), P305 + P351 + P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing), and P311 (Call a POISON CENTER/doctor).
How is 2,5-Dihydroxycinnamic acid methyl ester packed and shipped?
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This compound is typically supplied in crystalline form and stored at -20°C. TSS exports chemicals globally, adhering to all necessary regulations for safe and compliant international shipping.
How can I request a sample or quote for 2,5-Dihydroxycinnamic acid methyl ester?
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To request a sample or a quote, please contact the TSS sales department via our website or direct inquiry. Provide your contact details and the quantity required for a prompt response.
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