Acetylthiocholine chloride
Acetylthiocholine chloride (CAS: 6050-81-3), with the molecular formula CH₃COSCH₂CH₂N(CH₃)₃Cl and a molecular weight of 197.73 g/mol, is a thiocholine ester. This compound serves as a substrate for cholinesterases, playing a vital role in biochemical research, particularly in the study of enzyme kinetics and neurotransmission. It is commonly employed in neuroscience and cell biology for understanding cholinergic pathways and enzyme activity.
Cholinesterase Substrate
Acetylthiocholine chloride is widely used as a chromogenic or fluorogenic substrate for quantifying cholinesterase activity. Its enzymatic hydrolysis releases thiocholine, which can be detected spectrophotometrically.
Neuroscience Research
In neuroscience, this compound aids in the investigation of cholinergic neurotransmission and the function of acetylcholine esterase (AChE) and butyrylcholinesterase (BChE).
Enzyme Inhibition Studies
It is utilised in screening for inhibitors of cholinesterase enzymes, crucial for understanding mechanisms of action for certain drugs and toxins.
Biochemical Assays
Acetylthiocholine chloride is a standard reagent in various biochemical assays for enzyme characterisation and drug discovery.
| Molecular weight | 197.73 |
|---|---|
| Linear formula | CH3COSCH2CH2N(CH3)3Cl |
| Assay | ≥99% (TLC) |
| Form | powder |
| Storage temperature | −20°C |
Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ACHE(43) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Acetylthiocholine chloride used for?
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Acetylthiocholine chloride (CAS 6050-81-3) is primarily used as a substrate for cholinesterase enzymes in biochemical research, particularly for enzyme activity assays, studying neurotransmission, and screening for enzyme inhibitors.
What are the CAS number and formula for Acetylthiocholine chloride?
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The CAS number for Acetylthiocholine chloride is 6050-81-3, and its linear formula is CH₃COSCH₂CH₂N(CH₃)₃Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Acetylthiocholine chloride with an assay of ≥99% (TLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Acetylthiocholine chloride be handled safely?
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Acetylthiocholine chloride is classified as Danger (GHS05) and can cause serious eye damage (H318). Handle with appropriate personal protective equipment, including eye protection (P280, P305 + P351 + P338). Avoid contact with eyes.
How is Acetylthiocholine chloride shipped and exported?
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As a specialist global supplier, Tech Serve Solutions exports Acetylthiocholine chloride worldwide, adhering to all relevant shipping and safety regulations.
How can I request a quote or sample for Acetylthiocholine chloride?
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To request a quote or sample of Acetylthiocholine chloride, please contact the Tech Serve Solutions sales team via our website or listed contact details.
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