Acetylcholine bromide

CAS 66-23-9(CH3)3N(Br)CH2CH2OCOCH3Biochemicals & Reagents

Acetylcholine bromide (CAS 66-23-9) is a vital neurotransmitter with the linear formula (CH₃)₃N(Br)CH₂CH₂OCOCH₃ and a molecular weight of 226.11 g/mol. It functions as an acetylcholine receptor agonist, crucial for inducing muscle contractions by amplifying sarcolemma action potentials. This compound is also utilised as an inhibitor in the identification and characterisation of natural and mutated butyrylcholinesterases, playing a key role in neuroscience research and diagnostics.

IUPAC: ACh

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Acetylcholine bromide ((CH3)3N(Br)CH2CH2OCOCH3) — chemical structure, CAS 66-23-9; Life Science, fine chemical supplied by Tech Serve Solutions

AgonistsBiochemicals and ReagentsCell BiologyCholinergicsCholinesterase SubstratesEnzymesInhibitorsand SubstratesNeuroscienceNeurotransmission

01 /Applications

Acetylcholine Receptor Studies

Acts as an acetylcholine receptor agonist for identifying, characterising, and differentiating various types of cholinergic receptors. Essential for understanding neurotransmission and receptor pharmacology.

Enzyme Characterisation

Utilised as an inhibitor to identify and characterise both natural and mutated forms of butyrylcholinesterase. Aids in the study of enzyme kinetics and inhibition mechanisms.

Neuroscience Research

Serves as a key biochemical reagent in neuroscience, particularly for investigating cholinergic pathways and neurotransmitter functions. Supports research in cell signaling and neurodegenerative diseases.

02 /Properties

Molecular weight	226.11
Linear formula	(CH3)3N(Br)CH2CH2OCOCH3
Assay	≥99%
Storage temperature	−20°C
Application	Acetylcholine is an endogenous neurotransmitter at cholinergic synapses that amplifies action potential of the sarcolemma thereby inducing muscle contractions. Acetylcholine bromide is used as an acetylcholine receptor agonist to identify, characterize and differentiate among types of cholinergic receptors. Acetylcholine bromide is used as an inhibitor to identify and characterize natural and mutated butyrylcholinesterase(s).
Melting point	140-143 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

66-23-9

MDL number

MFCD00011814

PubChem substance

24891093

Beilstein registry

3572117

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Acetylcholine bromide used for?

Acetylcholine bromide is used as an acetylcholine receptor agonist for identifying and characterising cholinergic receptors and as an inhibitor for identifying and characterising butyrylcholinesterase variants.

What is the CAS number and formula for Acetylcholine bromide?

The CAS number for Acetylcholine bromide is 66-23-9 and its linear formula is (CH₃)₃N(Br)CH₂CH₂OCOCH₃.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Acetylcholine bromide with a minimum assay of 99%. This product is intended for research and technical use and is not represented as USP, BP, EP, or pharmacopoeia grade.

How should Acetylcholine bromide be handled safely?

Handle Acetylcholine bromide with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. It is a Warning substance that causes skin irritation, serious eye irritation, and may cause respiratory irritation (H315-H319-H335).

Is Acetylcholine bromide a controlled substance?

The provided data does not indicate that Acetylcholine bromide is a controlled substance.

How is Acetylcholine bromide supplied and exported?

Acetylcholine bromide is supplied by Tech Serve Solutions, a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.