2,5-Difluorobenzenesulfonyl chloride
2,5-Difluorobenzenesulfonyl chloride (CAS 26120-86-5), with the linear formula F2C6H3SO2Cl and a molecular weight of 212.60 g/mol, is a valuable organic fluorinated building block. It functions as a reactive intermediate, primarily utilised in chemical synthesis for the introduction of the 2,5-difluorobenzenesulfonyl moiety into target molecules. This compound serves as a key reagent in the development of various organic compounds, particularly within research and development settings.
- Synonyms
- F2C6H3SO2Cl

Synthesis of Fluorinated Organic Compounds
This sulfonyl chloride is a crucial intermediate for incorporating the 2,5-difluorobenzenesulfonyl group into complex organic molecules. Its reactivity allows for its use in creating novel fluorinated compounds with potential applications in pharmaceuticals and agrochemicals.
Reagent in Organic Synthesis
As a building block, it participates in various coupling and substitution reactions. It is employed in academic and industrial research laboratories for the construction of specialised organic structures.
Development of Novel Materials
The unique electronic properties conferred by the fluorine atoms make this compound a potential precursor for advanced materials. Researchers may utilise it in exploring new polymers or functional organic materials.
| Molecular weight | 212.60 |
|---|---|
| Linear formula | F2C6H3SO2Cl |
| Assay | 97% |
| Boiling point | 221 °C(lit.) |
| Density | 1.58 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.516(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Difluorobenzenesulfonyl chloride primarily used for?
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2,5-Difluorobenzenesulfonyl chloride is primarily used as a reactive intermediate and a building block in organic synthesis for the introduction of the 2,5-difluorobenzenesulfonyl moiety into target molecules, particularly in the development of novel fluorinated organic compounds.
What is the CAS number and formula for 2,5-Difluorobenzenesulfonyl chloride?
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The CAS number is 26120-86-5 and the linear formula is F2C6H3SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Difluorobenzenesulfonyl chloride with an assay of 97%. We do not represent this product as meeting any pharmacopoeia standards such as USP, BP, or EP.
How should 2,5-Difluorobenzenesulfonyl chloride be handled safely?
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This compound is classified as Danger, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including faceshields, full-face respirators, gloves, goggles, and suitable respirator filters (e.g., type ABEK), must be used. Handle in a well-ventilated area and follow all safety precautions.
How is 2,5-Difluorobenzenesulfonyl chloride packed and shipped?
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This chemical is packed according to international regulations for hazardous materials, including UN 3265, Hazard Class 8, Packing Group II. TSS exports globally, adhering to all relevant shipping and customs requirements.
How can I request a sample or quote for 2,5-Difluorobenzenesulfonyl chloride?
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To request a sample or a quotation, please contact our sales department through the website or by calling our direct line. Our team will be pleased to assist you with your requirements.
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