2,5-Difluorobenzaldehyde
2,5-Difluorobenzaldehyde (CAS 2646-90-4) is a fluorinated aromatic aldehyde with the molecular formula F₂C₆H₃CHO and a molecular weight of 142.10 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for the preparation of complex fluorinated molecules. It is often employed in chemical research and development for creating novel compounds with specific electronic or biological properties.
- Synonyms
- F2C6H3CHO2,5-Difluorobenzene-1-carbaldehyde
Synthesis of Fluorinated Analogues
2,5-Difluorobenzaldehyde is utilised in reactions such as the Henry condensation with nitroethane to synthesise fluorinated analogues. This process is crucial for developing new chemical entities with modified characteristics.
Building Block in Organic Chemistry
As a fluorinated aryl building block, this aldehyde is instrumental in constructing diverse organic molecules. Its reactivity allows for various derivatisations in the pursuit of novel chemical structures.
Research and Development
The compound finds application in R&D laboratories for exploring new synthetic pathways and creating specialised fluorinated intermediates. Its specific structure is beneficial for introducing fluorine atoms into target molecules.
| Molecular weight | 142.10 |
|---|---|
| Linear formula | F2C6H3CHO |
| Assay | 98% |
| Boiling point | 67-69 °C/17 mmHg(lit.) |
| Density | 1.308 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.498(lit.) |
| Application | 2,5-Difluorobenzaldehyde was used in the synthesis of fluorinated analog by Henry condensation with nitroethane1. |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 59 °C / 138.2 °F |
| Transport (UN / ADR) | UN 1989C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Difluorobenzaldehyde used for?
+
2,5-Difluorobenzaldehyde is primarily used as a building block in organic synthesis, particularly for creating fluorinated molecules and analogues via reactions like the Henry condensation.
What is the CAS number and formula for 2,5-Difluorobenzaldehyde?
+
The CAS number is 2646-90-4, and its linear formula is F₂C₆H₃CHO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,5-Difluorobenzaldehyde with a minimum assay of 98%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should 2,5-Difluorobenzaldehyde be handled safely?
+
Handle with appropriate personal protective equipment, including eyeshields and gloves. Due to its flammable nature (Flash Point 59 °C) and irritant properties (H226-H315-H319-H335), ensure good ventilation and avoid contact with skin, eyes, and clothing.
Is 2,5-Difluorobenzaldehyde available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,5-Difluorobenzaldehyde, serving customers worldwide.
How can I request a quote or sample?
+
To request a quote or a sample of 2,5-Difluorobenzaldehyde, please contact our sales team through the website or via the provided contact details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis