2,4,6-Triisopropylbenzenesulfonyl azide
2,4,6-Triisopropylbenzenesulfonyl azide (CAS: 36982-84-0) is a sophisticated organic compound with the molecular formula C15H23N3O2S and a molecular weight of 309.43 g/mol. This reagent is primarily utilised in advanced chemical synthesis for azidation and diazo transfer reactions. Its specific applications include stereoselective synthesis of functionalised saccharides and Meyer's lactamization, underscoring its utility in complex organic chemistry.
- IUPAC
- 2,4,6-Triisopropylphenylsulfonyl azide,2,4,6-Tris(1-methylethyl)-benzenesulfonyl azide
- Synonyms
- 36982-84-0C15H23N3O2S
Stereoselective Synthesis of Functionalised Saccharides
2,4,6-Triisopropylbenzenesulfonyl azide serves as a key reagent in the stereoselective diversity-oriented synthesis of functionalised saccharides, enabling precise control over carbohydrate structures.
Meyer's Lactamization
This compound is employed as a reagent in Meyer's lactamization, a valuable transformation for the synthesis of nitrogen-containing heterocyclic compounds.
Synthesis of Biological Agents
It finds application in the synthesis of various biologically relevant molecules, including antidotes for anthrax lethal factor intoxication, bacterial RNA polymerase inhibitors, and single enantiomers of mycobacterial keomycolic acids.
Peptide and Heterocycle Synthesis
The azide functionality allows for its use in constructing complex structures such as bicyclic extended dipeptide surrogates, contributing to the development of novel molecular scaffolds.
| Molecular weight | 309.43 |
|---|---|
| Empirical formula | C15H23N3O2S |
| Assay | 97% |
| Refractive index | n20/D 1.499 |
| Concentration | 10%±2% in toluene |
| Storage temperature | 2-8°C |
| Contains / stabiliser | 15 wt. % water as stabilizer |
| Melting point | 39-44 °C |
| Impurities tested | ≤0.015% water |
| Application | Reagent for:• Stereoselective diversity-oriented synthesis of functionalized saccharides1• Meyer′s lactamization2Reagent for synthesis of:• Antidote to anthrax lethal factor intoxication3• Bacterial RNA polymerase inhibitor4• Bicyclic extended dipeptide surrogates5• Single enantiomers of mycobacterial keomycolic acids6 |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4,6-Triisopropylbenzenesulfonyl azide used for?
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2,4,6-Triisopropylbenzenesulfonyl azide is used as a reagent for stereoselective diversity-oriented synthesis of functionalised saccharides, Meyer's lactamization, and the synthesis of various biologically active compounds.
What are the CAS number and formula for 2,4,6-Triisopropylbenzenesulfonyl azide?
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The CAS number is 36982-84-0, and its empirical formula (Hill notation) is C15H23N3O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4,6-Triisopropylbenzenesulfonyl azide with an assay of 97%. This is a technical/research grade chemical, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,4,6-Triisopropylbenzenesulfonyl azide be handled and stored?
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2,4,6-Triisopropylbenzenesulfonyl azide is classified as toxic if swallowed (H301) and requires careful handling. It should be stored at 2-8°C and is typically supplied as a 10%±2% solution in toluene, containing 15 wt.% water as a stabilizer. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information.
How is this product packed, shipped, and exported?
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This product is handled according to strict safety protocols and international shipping regulations for hazardous materials. Specific packaging and export documentation will be provided upon request, adhering to all relevant guidelines.
How can I request a sample or quote for 2,4,6-Triisopropylbenzenesulfonyl azide?
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To request a sample or a quotation, please contact our sales department via the website or by telephone, providing your contact details and the required quantity.
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