2,3-O-Isopropylidene-D-ribonic γ-lactone

CAS 30725-00-9C8H12O5Chemical Synthesis

2,3-O-Isopropylidene-D-ribonic γ-lactone (CAS: 30725-00-9), with a molecular formula of C8H12O5 and a molecular weight of 188.18 g/mol, is a key carbohydrate derivative. This compound is an important chiral building block, primarily utilised in complex organic synthesis. Its applications span the preparation of C-nucleosides, prostanoids, and GABA analogs, highlighting its significance in medicinal chemistry and the development of biologically active molecules.

IUPAC: 2,3-O-Isopropylidene-D-ribono-1,4-lactone
Synonyms: 2,3-O-Isopropylidene-D-ribono-1,4-lactoneC8H12O5

Email us

2,3-O-Isopropylidene-D-ribonic γ-lactone (C8H12O5) — chemical structure, CAS 30725-00-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Carbohydrate ChemistryCarbohydrate DerivativesChemical BiologyChemical Synthesis

01 /Applications

Synthesis of C-Nucleosides

This lactone serves as a critical starting material for the synthesis of C-nucleosides, a class of compounds with potential antiviral and anticancer activities. Notable examples include the preparation of neplanocin A.

Preparation of Prostanoids

The compound is employed in the synthetic routes towards prostanoids, which are lipid compounds involved in numerous physiological processes. Its chiral nature is essential for creating the stereochemically defined structures required for these molecules.

Development of GABA Analogs

Utilised in the preparation of GABA analogs via homochiral 2-piperidones, this lactone contributes to the synthesis of molecules that modulate neurotransmission, potentially for therapeutic applications.

02 /Properties

Molecular weight	188.18
Empirical formula	C8H12O5
Assay	99%
Optical activity	[α]20/D −69°, c = 2 in pyridine
Application	Important raw material for the synthesis of C-nucleosides,1 prostanoids,2 and GABA analogs via homochiral 2-piperidones.3 Starting material for the preparation of biochemical compounds including C-nucleosides, such as neplanocin A, and GABA analogs, via homochiral 2-piperidones.4,5,6
Melting point	135-138 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

30725-00-9

MDL number

MFCD00080793

PubChem substance

24863253

Beilstein registry

10090

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,3-O-Isopropylidene-D-ribonic γ-lactone used for?

It is primarily used as an important raw material for the synthesis of C-nucleosides, prostanoids, and GABA analogs via homochiral 2-piperidones.

What is the CAS number and chemical formula for 2,3-O-Isopropylidene-D-ribonic γ-lactone?

The CAS number is 30725-00-9 and the empirical formula is C8H12O5.

What grade and purity does Tech Serve Solutions supply for 2,3-O-Isopropylidene-D-ribonic γ-lactone?

Tech Serve Solutions supplies 2,3-O-Isopropylidene-D-ribonic γ-lactone with an assay of 99%. This is typically considered a research or technical grade material and is not represented as USP, BP, or EP.

What are the key safety and handling considerations for this compound?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified with WGK Germany 3, indicating a high hazard to water.

How is 2,3-O-Isopropylidene-D-ribonic γ-lactone packed, shipped, and exported?

Tech Serve Solutions reliably packs, ships, and exports fine chemicals globally, adhering to all necessary regulations for safe and secure transport.

How can I request a sample or quote for this product?

To request a sample or quote, please visit the Tech Serve Solutions website or contact our sales team directly, providing the product name and CAS number (30725-00-9).