2,3,5-Trichlorobenzaldehyde

CAS 56961-75-2Cl3C6H2CHOChemical Synthesis

2,3,5-Trichlorobenzaldehyde (CAS 56961-75-2) is a chlorinated aromatic aldehyde with the molecular formula Cl3C6H2CHO and a molecular weight of 209.46 g/mol. It is primarily utilised as a chemical intermediate in organic synthesis. Applications include its use in the preparation of pharmaceuticals, such as the sodium channel blocker GW356194, and in material science for the functionalisation of polymer surfaces.

Synonyms: 56961-75-2Cl3C6H2CHO

Email us

2,3,5-Trichlorobenzaldehyde (Cl3C6H2CHO) — chemical structure, CAS 56961-75-2; Chemistry, fine chemical supplied by Tech Serve Solutions

AldehydesBuilding BlocksCarbonyl CompoundsChemical Synthesis

01 /Applications

Pharmaceutical Synthesis

2,3,5-Trichlorobenzaldehyde serves as a key intermediate in the synthesis of active pharmaceutical ingredients. Notably, it has been employed in the preparation of α-keto amides, which are crucial for the development of sodium channel blockers like GW356194.

Materials Science and Surface Modification

This compound is utilised for labelling amine groups on modified polymer surfaces. For instance, it has been applied to brominated mercat-modified poly(tetrafluoroethylene-co-hexafluoropropylene) thin films, enabling surface functionalisation.

Organic Building Block

As a versatile building block, 2,3,5-Trichlorobenzaldehyde offers a reactive aldehyde group on a trichlorinated benzene ring, facilitating diverse synthetic transformations in organic chemistry.

02 /Properties

Molecular weight	209.46
Linear formula	Cl3C6H2CHO
Assay	98%
Application	2,3,5-Trichlorobenzaldehyde has been used:• in the synthesis of α-keto amide, a key intermediate in the synthesis of the sodium channel blocker, GW3561941• for labelling of amine groups of brominated mercat-modified poly(tetrafluoroethylene-co-hexafluoropropylene) thin films2
Melting point	73-75 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

56961-75-2

MDL number

MFCD00010860

PubChem substance

24857577

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,3,5-Trichlorobenzaldehyde used for?

2,3,5-Trichlorobenzaldehyde is used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals like GW356194 and in materials science for surface modification of polymers.

What are the CAS number and formula for 2,3,5-Trichlorobenzaldehyde?

The CAS number is 56961-75-2 and the linear formula is Cl3C6H2CHO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2,3,5-Trichlorobenzaldehyde with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.

How should 2,3,5-Trichlorobenzaldehyde be handled safely?

2,3,5-Trichlorobenzaldehyde is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area. Refer to the Safety Data Sheet for full details.

Is 2,3,5-Trichlorobenzaldehyde a controlled substance?

The provided data does not indicate that 2,3,5-Trichlorobenzaldehyde is a controlled substance.

How is 2,3,5-Trichlorobenzaldehyde packed and shipped?

Information regarding specific packing and shipping procedures is available upon request. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.